Cremonese was in Serie A in its first season (1929–30) but entered a long period of decline, languishing in the lower leagues before the late 1970s. By 1984 they had achieved promotion to Serie A, with one-year spells in 1984–85, 1989–90 and 1991–92.
Cremonese had a successful run in the 1992/93 Anglo-Italian Cup, beating Bari 4-1 in the semi-final, and Derby County 3-1 in the final at the old Wembley Stadium: Cremonese's scorers were Corrado Verdelli, Riccardo Maspero and Andrea Tentoni, with Derby's goal scored by Marco Gabbiadini.
Relegation resulted in the decline of the club, plummeting to Serie C2 by 2000 before achieving successive promotions back to Serie B by 2005. Giovanni Dall'Igna, another defender from the Serie A years, has since returned to the club. However, Cremonese were relegated to Serie C1 in the 2005/2006 season. Cremonese have tried to return to Serie B since: their best attempt was in the 2009/10 season, when they were beaten by Varese in the promotion play-off final (2-1 on aggregate).