Talk:Caffeine: Difference between revisions
ClueBot III (talk | contribs) m Archiving 1 discussion to Talk:Caffeine/Archive 6. (BOT) |
→assorted problems: new section |
||
Line 98: | Line 98: | ||
Cheers.—[[User:InternetArchiveBot|'''<span style="color:darkgrey;font-family:monospace">InternetArchiveBot</span>''']] <span style="color:green;font-family:Rockwell">([[User talk:InternetArchiveBot|Report bug]])</span> 16:59, 12 November 2016 (UTC) |
Cheers.—[[User:InternetArchiveBot|'''<span style="color:darkgrey;font-family:monospace">InternetArchiveBot</span>''']] <span style="color:green;font-family:Rockwell">([[User talk:InternetArchiveBot|Report bug]])</span> 16:59, 12 November 2016 (UTC) |
||
== assorted problems == |
|||
Addiction - some degree of aversion may actually occur, which? (with?) people preferring placebo |
|||
Effects of genetics - and beta-1 and beta-2 play roles - beta-1 & beta-2 should be fully identified here (rather than in a following sentence). |
|||
people with the heterozygote? (heterozygous?) ADR beta-2 |
|||
Beta 2- (is it beta-2, beta2, or beta 2? - be consistent) adrenoceptors are receptors that regulate glycogenolysis, secret? insulin (insulin secretion,?) and intramusculatly transport? (intramuscular transport of? - I doubt the receptor transports insulin or glucose itself) glucose |
|||
Arg389 homozygotes? (homozygous?) subjects |
|||
altered norepinephrine (an adrenoceptor agonist) neurotransmission contribute? (contributes?) to |
|||
Biosynthesis - The text describes chemical synthesis, not biosynthesis. |
|||
Figure - lab synthesis - where does the nitroso (NO) group come from? |
|||
Analogs - have also been elucidated? (identified?). |
|||
Products - and inhalation? (inhalants?). |
|||
Caffeine content in select food and drugs - 12 fl. oz. Coca-Cola Classic is listed as 34 mg and 96 mg/L but the same size Guarana Antarctica is given as 30 mg (less) and 100 mg/L (more - inconsistent). |
|||
[[Special:Contributions/69.72.92.65|69.72.92.65]] ([[User talk:69.72.92.65|talk]]) 06:36, 6 February 2017 (UTC) |
Revision as of 06:36, 6 February 2017
This is the talk page for discussing improvements to the Caffeine article. This is not a forum for general discussion of the article's subject. |
Article policies
|
Find sources: Google (books · news · scholar · free images · WP refs) · FENS · JSTOR · TWL |
Archives: Index, 1, 2, 3, 4, 5, 6, 7Auto-archiving period: 90 days |
Caffeine is a former featured article. Please see the links under Article milestones below for its original nomination page (for older articles, check the nomination archive) and why it was removed. | ||||||||||||||||||||||
This article appeared on Wikipedia's Main Page as Today's featured article on September 16, 2006. | ||||||||||||||||||||||
|
This article is of interest to multiple WikiProjects. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Please add the quality rating to the {{WikiProject banner shell}} template instead of this project banner. See WP:PIQA for details.
Please add the quality rating to the {{WikiProject banner shell}} template instead of this project banner. See WP:PIQA for details.
Please add the quality rating to the {{WikiProject banner shell}} template instead of this project banner. See WP:PIQA for details.
Please add the quality rating to the {{WikiProject banner shell}} template instead of this project banner. See WP:PIQA for details.
|
This article is written in American English, which has its own spelling conventions (color, defense, traveled) and some terms that are used in it may be different or absent from other varieties of English. According to the relevant style guide, this should not be changed without broad consensus. |
Toolbox |
---|
Self-assembly of Caffeine
Caffeine is known to exist in different polymorphic form. It has been shown that an anhydrous form of caffeine can undergo supramolecular self-assembly leading to gelation in alcoholic solvents including ethanol at very low concentration (1). This might bring some new application of caffeine in materials science.
(1) Nonappa; Kolehmainen, E. Caffeine as a Gelator. Gels 2016, 2, 9. — Preceding unsigned comment added by Nonappa (talk • contribs) 17:40, 3 March 2016 (UTC)
- Are you proposing this be added to the "Research" section? Sizeofint (talk) 19:18, 3 March 2016 (UTC)
Review
... of risks and benefits for neurological disease doi:10.1136/practneurol-2015-001162 JFW | T@lk 22:44, 16 March 2016 (UTC)
Semi-protected edit request on 8 August 2016
This edit request has been answered. Set the |answered= or |ans= parameter to no to reactivate your request. |
In the Physical and chemical properties, the line "It is weakly basic (pKa = ~0.6) requiring strong acid to protonate it.[138]" is incorrect, I would suggest changing it to:
"It is weakly basic (pKb = ~0.6) requiring strong acid to protonate it.[138]" and not referencing the book but the paper directly (see below).
The pKa value for caffeine is around 14:
I followed the citation 138 and in the book "Harry G. Brittain; Richard J. Prankerd (2007). Profiles of Drug Substances, Excipients and Related Methodology, volume 33: Critical Compilation of pKa Values for Pharmaceutical Substances. Academic Press. p. 15. ISBN 0-12-260833-X. Retrieved 15 January 2014." on the page 106 values of pKa for caffeine are indeed -0.13 and 0.18 - this is also incorrect, thus it would suggest that caffeine is an acid comparable in strengt to e.g. TFA. The table on the page 106 points out to the paper by ROBERT L. BENOIT AND MONIQUE FRECHEIT "Protonation of hypoxanthine, guanine, xanthine, and caffeine". In the paper, it were the pKb values that were measured not pKa (as stated in the last line of the abstract).
212.87.10.2 (talk) 12:54, 8 August 2016 (UTC)
- I did a CTRL-F in that paper [1] and I'm not seeing where it has the 0.6 figure. Sizeofint (talk) 17:27, 8 August 2016 (UTC)
- Not done: Like Sizeofint I cannot find anything in the article to support that change. The sheet does say the pKa is 14, but there's nothing about 0.6 in the pdf and there's no "pKb" either. EvergreenFir (talk) 01:02, 9 August 2016 (UTC)
Contradiction
In the lead, it says caffeine may be used to treat pulmonary dysplasia of prematurity and prevent apnoea of prematurity, then in the next section that it is used to treat or prevent pulmonary dysplasia of prematurity and treat, but not prevent, apnoea of prematurity. Which is correct? At least I try (talk) 03:03, 21 August 2016 (UTC)
- I think the article is correct, fixed the lead. Sizeofint (talk) 04:09, 21 August 2016 (UTC)
External links modified
Hello fellow Wikipedians,
I have just modified one external link on Caffeine. Please take a moment to review my edit. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit this simple FaQ for additional information. I made the following changes:
- Added archive https://web.archive.org/web/20150815050402/http://www.dsm5.org/Documents/Substance%20Use%20Disorder%20Fact%20Sheet.pdf to http://www.dsm5.org/documents/substance%20use%20disorder%20fact%20sheet.pdf
When you have finished reviewing my changes, please set the checked parameter below to true or failed to let others know (documentation at {{Sourcecheck}}
).
This message was posted before February 2018. After February 2018, "External links modified" talk page sections are no longer generated or monitored by InternetArchiveBot. No special action is required regarding these talk page notices, other than regular verification using the archive tool instructions below. Editors have permission to delete these "External links modified" talk page sections if they want to de-clutter talk pages, but see the RfC before doing mass systematic removals. This message is updated dynamically through the template {{source check}}
(last update: 5 June 2024).
- If you have discovered URLs which were erroneously considered dead by the bot, you can report them with this tool.
- If you found an error with any archives or the URLs themselves, you can fix them with this tool.
Cheers.—InternetArchiveBot (Report bug) 16:59, 12 November 2016 (UTC)
assorted problems
Addiction - some degree of aversion may actually occur, which? (with?) people preferring placebo Effects of genetics - and beta-1 and beta-2 play roles - beta-1 & beta-2 should be fully identified here (rather than in a following sentence). people with the heterozygote? (heterozygous?) ADR beta-2 Beta 2- (is it beta-2, beta2, or beta 2? - be consistent) adrenoceptors are receptors that regulate glycogenolysis, secret? insulin (insulin secretion,?) and intramusculatly transport? (intramuscular transport of? - I doubt the receptor transports insulin or glucose itself) glucose Arg389 homozygotes? (homozygous?) subjects altered norepinephrine (an adrenoceptor agonist) neurotransmission contribute? (contributes?) to Biosynthesis - The text describes chemical synthesis, not biosynthesis. Figure - lab synthesis - where does the nitroso (NO) group come from? Analogs - have also been elucidated? (identified?). Products - and inhalation? (inhalants?). Caffeine content in select food and drugs - 12 fl. oz. Coca-Cola Classic is listed as 34 mg and 96 mg/L but the same size Guarana Antarctica is given as 30 mg (less) and 100 mg/L (more - inconsistent). 69.72.92.65 (talk) 06:36, 6 February 2017 (UTC)
- Wikipedia former featured articles
- Featured articles that have appeared on the main page
- Featured articles that have appeared on the main page once
- Old requests for peer review
- B-Class pharmacology articles
- High-importance pharmacology articles
- WikiProject Pharmacology articles
- B-Class chemicals articles
- Mid-importance chemicals articles
- B-Class WPChem worklist articles
- B-Class neuroscience articles
- High-importance neuroscience articles
- B-Class Food and drink articles
- High-importance Food and drink articles
- WikiProject Food and drink articles
- Wikipedia articles that use American English