Valnemulin

Valnemulin
Clinical data
Trade names	Econor
AHFS/Drugs.com	International Drug Names
Routes of; administration	oral (in-feed)
ATCvet code	QJ01XQ02 (WHO) ;
Legal status
Legal status	Veterinary use only;
Identifiers
	IUPAC name (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyl-; 5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-; 3a,9-propano-3aH-cyclopenta[8]annulen-8-yl-; [(R)-2-(2-amino-3-methylbutanoylamino)-1,1-dimethtylethyl; sulfanyl]acetate;
CAS Number	101312-92-9 ;
PubChem CID	127791;
ChemSpider	8026591 ;
UNII	2AHC415BQG;
ChEMBL	ChEMBL1688852 ;
CompTox Dashboard (EPA)	DTXSID2046751 ;
Chemical and physical data
Formula	C31H52N2O5S
Molar mass	564.83 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(NCC(SCC(=O)O[C@@H]2C[C@@](\C=C)([C@@H](O)[C@@H]([C@]31[C@@H](C(=O)CC1)[C@@]2(C)[C@H](C)CC3)C)C)(C)C)[C@H](N)C(C)C;
	InChI InChI=1S/C31H52N2O5S/c1-10-29(8)15-22(38-23(35)16-39-28(6,7)17-33-27(37)24(32)18(2)3)30(9)19(4)11-13-31(20(5)26(29)36)14-12-21(34)25(30)31/h10,18-20,22,24-26,36H,1,11-17,32H2,2-9H3,(H,33,37)/t19-,20+,22-,24-,25+,26+,29-,30+,31+/m1/s1 ; Key:LLYYNOVSVPBRGV-MVNKZKPCSA-N ;
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Valnemulin (trade name Econor) is a pleuromutilin antibiotic used to treat swine dysentery, ileitis, colitis and pneumonia. It is also used for the prevention of intestinal infections of swine.^[1] Valnemulin has been observed to induce a rapid reduction of clinical symptoms of Mycoplasma bovis infection, and eliminate M. bovis from the lungs of calves.^[2]

References

^ Econor: Product Profile
^ Stipkovits L, Ripley PH, Tenk M, Glávits R, Molnár T, Fodor L (June 2005). "The efficacy of valnemulin (Econor) in the control of disease caused by experimental infection of calves with Mycoplasma bovis". Research in Veterinary Science. 78 (3): 207–15. doi:10.1016/j.rvsc.2004.09.005. PMID 15766939.

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[1] Econor: Product Profile

[2] Stipkovits L, Ripley PH, Tenk M, Glávits R, Molnár T, Fodor L (June 2005). "The efficacy of valnemulin (Econor) in the control of disease caused by experimental infection of calves with Mycoplasma bovis". Research in Veterinary Science. 78 (3): 207–15. doi:10.1016/j.rvsc.2004.09.005. PMID 15766939.

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