Phaclofen

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by Nemo bis (talk | contribs) at 16:32, 26 July 2019 (Removed URL that duplicated unique identifier. | You can use this tool yourself. Report bugs here.). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Phaclofen
Names
IUPAC name
[3-amino-2-(4-chlorophenyl)propyl]phosphonic acid
Identifiers
3D model (JSmol)
ChemSpider
  • InChI=1S/C9H13ClNO3P/c10-9-3-1-7(2-4-9)8(5-11)6-15(12,13)14/h1-4,8H,5-6,11H2,(H2,12,13,14) ☒N
    Key: VSGNGLJPOGUDON-UHFFFAOYSA-N ☒N
  • InChI=1/C9H13ClNO3P/c10-9-3-1-7(2-4-9)8(5-11)6-15(12,13)14/h1-4,8H,5-6,11H2,(H2,12,13,14)
    Key: VSGNGLJPOGUDON-UHFFFAOYAO
  • C1=CC(=CC=C1C(CN)CP(=O)(O)O)Cl
Properties
C9H13ClNO3P
Molar mass 249.631 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Phaclofen, or phosphonobaclofen, is a selective antagonist for the GABAB receptor.[1]

References

  1. ^ David I.B. KerrCorresponding author contact information, Jennifer Ong, Rolf H. Prager, Bruce D. Gynther, David R. Curtis (3 March 1987). "Phaclofen: a peripheral and central baclofen antagonist". Brain Research. 405: 150–154. doi:10.1016/0006-8993(87)90999-1. {{cite journal}}: |author= has generic name (help)CS1 maint: multiple names: authors list (link)