Censavudine

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Censavudine
Censavudine skeletal.svg
Censavudine ball-and-stick model.png
Clinical data
Synonyms 4'-ethynylstavudine, festinavir
Legal status
Legal status
  • Investigational
Identifiers
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
NIAID ChemDB
Chemical and physical data
Formula C12H12N2O4
Molar mass 248.235 g/mol
3D model (JSmol)

Censavudine (INN),[1] is an investigational new drug being developed by Bristol Myers-Squibb for the treatment of HIV infection. Censavudine is a nucleoside reverse transcriptase inhibitor that is active against HIV resistant to both abacavir and tenofovir, making the drug a candidate for people with multi-drug resistant (MDR) strains of the virus. Censavudine is a derivative of stavudine (d4T), but is less toxic.[medical citation needed] It was originally developed at Yale University.[2]

Renaming[edit]

Until 2013, censavudine has been known as festinavir, but the name was changed to avoid confusion with HIV protease inhibitors which all bear class suffix "–navir" (e.g. tipranavir, lopinavir, saquinavir etc.).

References[edit]