HslU—HslV peptidase
| HslU—HslV peptidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.4.25.2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
HslU—HslV peptidase (EC 3.4.25.2, HslUV, HslV-HslU, HslV peptidase, ATP-dependent HslV-HslU proteinase, caseinolytic protease X, caseinolytic proteinase X, ClpXP ATP-dependent protease, ClpXP protease, ClpXP serine proteinase, Escherichia coli ClpXP serine proteinase, HslUV protease, HslUV proteinase, HslVU protease, HslVU proteinase, protease HslVU, proteinase HslUV) is an enzyme.[1][2][3][4][5][6][7] This enzyme catalyses the following chemical reaction
- ATP-dependent cleavage of peptide bonds with broad specificity.
This enzyme belongs to the peptidase family T1.
References
- ^ Wang, J., Rho, S.H., Park, H.H. and Eom, S.H. (2005). "Correction of X-ray intensities from an HslV-HslU co-crystal containing lattice-translocation defects". Acta Crystallogr. D Biol. Crystallogr. 61: 932–941. doi:10.1107/s0907444905009546. PMID 15983416.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Nishii, W. and Takahashi, K. (2003). "Determination of the cleavage sites in SulA, a cell division inhibitor, by the ATP-dependent HslVU protease from Escherichia coli". FEBS Lett. 553: 351–354. doi:10.1016/s0014-5793(03)01044-5. PMID 14572649.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Ramachandran, R., Hartmann, C., Song, H.K., Huber, R. and Bochtler, M. (2002). "Functional interactions of HslV (ClpQ) with the ATPase HslU (ClpY)". Proc. Natl. Acad. Sci. USA. 99: 7396–7401. doi:10.1073/pnas.102188799. PMID 12032294.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Yoo, S.J., Seol, J.H., Shin, D.H., Rohrwild, M., Kang, M.S., Tanaka, K., Goldberg, A.L. and Chung, C.H. (1996). "Purification and characterization of the heat shock proteins HslV and HslU that form a new ATP-dependent protease in Escherichia coli". J. Biol. Chem. 271: 14035–14040. doi:10.1074/jbc.271.24.14035. PMID 8662828.
{{cite journal}}: CS1 maint: multiple names: authors list (link) CS1 maint: unflagged free DOI (link) - ^ Yoo, S.J., Seol, J.H., Seong, I.S., Kang, M.S. and Chung, C.H. (1997). "ATP binding, but not its hydrolysis, is required for assembly and proteolytic activity of the HslVU protease in Escherichia coli". Biochem. Biophys. Res. Commun. 238: 581–585. doi:10.1006/bbrc.1997.7341. PMID 9299555.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Kanemori, M., Nishihara, K., Yanagi, H. and Yura, T. (1997). "Synergistic roles of HslVU and other ATP-dependent proteases in controlling in vivo turnover of σ32 and abnormal proteins in Escherichia coli". J. Bacteriol. 179: 7219–7225. PMID 9393683.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Burton, R.E., Baker, T.A. and Sauer, R.T. (2005). "Nucleotide-dependent substrate recognition by the AAA+ HslUV protease". Nat. Struct. Mol. Biol. 12: 245–251. doi:10.1038/nsmb898. PMID 15696175.
{{cite journal}}: CS1 maint: multiple names: authors list (link)
External links
- HslU---HslV+peptidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)