Mozavaptan

Mozavaptan
Clinical data
Routes of; administration	Oral
ATC code	none;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name N-[4-(5-Dimethylamino-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)phenyl]-2-methylbenzamide;
CAS Number	137975-06-5 ;
PubChem CID	119369;
IUPHAR/BPS	2197;
ChemSpider	106618 ;
UNII	17OJ42922Y;
ChEMBL	ChEMBL420762 ;
CompTox Dashboard (EPA)	DTXSID8057641 ;
Chemical and physical data
Formula	C27H29N3O2
Molar mass	427.53 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC1=CC=CC=C1C(=O)NC2=CC=C(C=C2)C(=O)N3CCCC(C4=CC=CC=C43)N(C)C;
	InChI InChI=1S/C27H29N3O2/c1-19-9-4-5-10-22(19)26(31)28-21-16-14-20(15-17-21)27(32)30-18-8-13-24(29(2)3)23-11-6-7-12-25(23)30/h4-7,9-12,14-17,24H,8,13,18H2,1-3H3,(H,28,31) ; Key:WRNXUQJJCIZICJ-UHFFFAOYSA-N ;
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Mozavaptan (INN) is a vasopressin receptor antagonist marketed by Otsuka. In Japan, it was approved in October 2006 for hyponatremia (low blood sodium levels) caused by syndrome of inappropriate antidiuretic hormone (SIADH) due to ADH producing tumors.

References

H. Spreitzer (November 20, 2006). "Neue Wirkstoffe - Conivaptan". Österreichische Apothekerzeitung (in German) (24/2006).
Prous Science: Molecule of the Month November 2006

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