The organization is mostly run by volunteers and has its roots in the squatting movement. The original building was squatted in 1984 and "legalized" in 1989. Next to the concert hall, as part of the Binnepret complex, there's also a café (called the Kasbah), a restaurant (called MKZ), a library (Bollox), theatre for children (Kinderpret), a bike workshop (Farafina), a sauna (Fenomeen, discontinued in 2011), rehearsal studios, and a big courtyard.
The building the OCCII resides in was built as a horse tram garage with stables in 1883-84 by architect Abraham Salm (1857-1915), who also designed (together with his father G. B. Salm) the buildings where popular commercial venues Melkweg and Paradiso now operate.
The OCCII has no central programming, instead there are several programming groups that set the agenda. Some of these groups are Le Club Suburbia (mostly indie and post-punk), Hex (new wave and gothic), Muziek Kapot Moet (experimental music, electronic, noise, weird pop), Spellbound (electronic, dance), The Real Amsterdam Underground (punk, hardcore, crust) and Cool Schmool (dance, indie, riot grrrl, mostly female fronted).
In 2011, OCCII was listed as one of the ten best gig venues in Amsterdam.