SERPINB9

SERPINB9
Identifiers
Aliases	SERPINB9, CAP-3, CAP3, PI-9, PI9, serpin family B member 9
External IDs	OMIM: 601799; MGI: 106603; HomoloGene: 37888; GeneCards: SERPINB9; OMA:SERPINB9 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	2,903,309 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	33,201,940 bp
RNA expression pattern
	Top expressed in
	epithelium of nasopharynx; ; mononuclear cell; ; monocyte; ; germinal epithelium; ; appendix; ; lymph node; ; placenta; ; tibial nerve; ; blood; ; granulocyte;
	Top expressed in
	right lung lobe; ; gastrula; ; left lung; ; mesenteric lymph nodes; ; left lung lobe; ; placenta; ; lumbar spinal ganglion; ; Epithelium of choroid plexus; ; carotid body; ; spleen;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	peptidase inhibitor activity; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; protease binding; protein binding; serine-type endopeptidase inhibitor activity;
Cellular component	cytosol; membrane; intracellular anatomical structure; extracellular exosome; nucleus; cytoplasm; extracellular space; nucleoplasm; Golgi apparatus; collagen-containing extracellular matrix;
Biological process	negative regulation of peptidase activity; mast cell mediated immunity; negative regulation of apoptotic process; protection from natural killer cell mediated cytotoxicity; cellular response to estrogen stimulus; positive regulation of gene expression; negative regulation by symbiont of host apoptotic process; immune response; negative regulation of endopeptidase activity; apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;
	Sources:Amigo / QuickGO
Orthologs
	5272
	20723
	ENSG00000170542
	ENSMUSG00000045827
	P50453
	O08797
	NM_004155
	NM_009256
	NP_004146; NP_004146.1
	NP_033282
	Wikidata
View/Edit Human	View/Edit Mouse

Serpin B9 is a protein that in humans is encoded by the SERPINB9 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000170542 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000045827 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Sprecher CA, Morgenstern KA, Mathewes S, Dahlen JR, Schrader SK, Foster DC, Kisiel W (Jan 1996). "Molecular cloning, expression, and partial characterization of two novel members of the ovalbumin family of serine proteinase inhibitors". J Biol Chem. 270 (50): 29854–61. doi:10.1074/jbc.270.50.29854. PMID 8530382.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ Sun J, Stephens R, Mirza G, Kanai H, Ragoussis J, Bird PI (Feb 1999). "A serpin gene cluster on human chromosome 6p25 contains PI6, PI9 and ELANH2 which have a common structure almost identical to the 18q21 ovalbumin serpin genes". Cytogenet Cell Genet. 82 (3–4): 273–7. doi:10.1159/000015118. PMID 9858835.
^ "Entrez Gene: SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9".

External links

The MEROPS online database for peptidases and their inhibitors: I04.014
SERPINB9+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Template:PBB Controls

This article on a gene on human chromosome 6 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000170542 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000045827 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8530382-5] Sprecher CA, Morgenstern KA, Mathewes S, Dahlen JR, Schrader SK, Foster DC, Kisiel W (Jan 1996). "Molecular cloning, expression, and partial characterization of two novel members of the ovalbumin family of serine proteinase inhibitors". J Biol Chem. 270 (50): 29854–61. doi:10.1074/jbc.270.50.29854. PMID 8530382.{{cite journal}}: CS1 maint: unflagged free DOI (link)

[pmid9858835-6] Sun J, Stephens R, Mirza G, Kanai H, Ragoussis J, Bird PI (Feb 1999). "A serpin gene cluster on human chromosome 6p25 contains PI6, PI9 and ELANH2 which have a common structure almost identical to the 18q21 ovalbumin serpin genes". Cytogenet Cell Genet. 82 (3–4): 273–7. doi:10.1159/000015118. PMID 9858835.

[entrez-7] "Entrez Gene: SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9".

[1]

[2]

[3]

[4]

[5]

[6]

[7]

v t e Serpins
inhibitory	Alpha 1-antichymotrypsin Alpha 1-antitrypsin Alpha 2-antiplasmin Antithrombin C1-inhibitor Heparin cofactor II Protein C inhibitor Plasminogen activator inhibitor-1 Plasminogen activator inhibitor-2 Protein Z-related protease inhibitor SERPINA1 SERPINA2 SERPINA3 SERPINA4 SERPINA5 SERPINA9 SERPINA14 SERPINB1 SERPINB2 SERPINB3 SERPINB4 SERPINB5 SERPINB6 SERPINB7 SERPINB8 SERPINB9 SERPINB10 SERPINB13 SERPINC1 SERPIND1 SERPINE1 SERPINE2 SERPINE2 SERPINF1 SERPING1 SERPINH1 SERPINI1 SERPINI2
Cross class inhibitory	MENT SCCA-1 CrmA
noninhibitory	Heat shock protein 47 Maspin Ovalbumin Transcortin Thyroxine-binding globulin Angiotensinogen PEDF
see also disorders of globin and globulin proteins

SERPINB9

See also

References

Further reading

External links