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IUPAC name
2-methyl-1-nitro-3-[(tetrahydro-3-furanyl) methyl] guanidine
Other names
(RS)-1-methyl-2-nitro-3-[(tetrahydro-3-furanyl) methyl] guanidine; MTI-446
165252-70-0 N
ChEBI CHEBI:39183 YesY
ChemSpider 171124 YesY
Jmol-3D images Image
KEGG C18509 YesY
PubChem 197701
Molar mass 202.21 g·mol−1
Melting point 107.5
39.83 g/L
≥2000 mg/kg (oral, rat and mouse)[1]
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N verify (what isYesY/N?)
Infobox references

Dinotefuran is an insecticide of the neonicotinoid class developed by Mitsui Chemicals for control of insect pests such as aphids, whiteflies, thrips, leafhoppers, leafminers, sawflies, mole cricket, white grubs, lacebugs, billbugs, beetles, mealybugs, and cockroaches on leafy vegetables, in residential and commercial buildings, and for professional turf management.[2] Its mechanism of action involves disruption of the insect's nervous system by inhibiting nicotinic acetylcholine receptors. In order to avoid harming beneficial insects such as bees, it should not be applied during bloom. [3]

In July of 2013, the state of Oregon temporarily restricted the use of dinotefuran pending the results of an investigation into a large bee kill.[4]

Dinotefuran is also used in veterinary medicine as a flea and tick preventative for dogs and as a flea preventative for cats. It is used in combination with pyriproxifen or permethrin.