Hypomide

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Hypomide was a stable formulation of hypochlorous acid used as a hand and surface sanitizer in both the hospital and home environment. Before the advent of Hypomide, hypochlorous acid had limited use in the healthcare environment because its instability necessitated in-situ production by electrolysis involving special equipment. Nevertheless, its potency as an antimicrobial agent was recognised and hypochlorous acid is often relied upon by dentists, for example, to clean their tools and instruments. It is no longer commercially available.

Specifications[edit]

Because hypochlorous acid kills microorganisms at very low concentrations (e.g. it is bactericidal at between 0.1 and 10 parts per million) it can be presented at less than 1% solution in saline and yet remain highly effective. It provides a 7 log10 reduction in a wide range of commonly encountered microorganisms, including gram positive and gram negative bacteria (even multi-resistant strains such as MRSA), fungi and viruses. A 7 log10 reduction equates to 99.99999% kill rate: 100 times greater than the required pass rate on the BS:EN 1276 standard test for sanitizers and disinfectants. Even against difficult-to-treat spores, such as the dangerous Clostridium difficile, Hypomide achieves a 5 log10 kill rate.[1]

Uses[edit]

Hypochlorous acid is non-toxic and is not an irritant.[2][3][4]

References[edit]

  1. ^ Hospital Infection Research Laboratory. Queen Elizabeth Hospital, Birmingham. July 2010
  2. ^ Wang L et al. Hypochlorous acid as a potential wound care agent. Part I Stabilized hypochlorous acid: a component of the inorganic armamentarium of innate immunity. J Burns and Wounds 2007;April:65-79.
  3. ^ Robson MC et al. Hypochlorous acid as a potential wound care agent. Part II Stabilized hypochlorous acid: its role in decreasing tissue bacterial bioburden and overcoming the inhibition of infection on wound haling. J Burns and Wounds 2007;April:80-90.
  4. ^ Selkon JB et al 2006. Evaluation of hypochlorous acid washes in the treatment of venous leg ulcers. J Wound Care 2006: 15:33-37.