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Systematic (IUPAC) name
Clinical data
Legal status ?
CAS number 116313-94-1
ATC code None
PubChem CID 5464105
ChemSpider 4576539
Chemical data
Formula C12H11NO6 
Mol. mass 265.219 g/mol

Nitecapone (INN; OR-462) is a drug which acts as a selective inhibitor of the enzyme catechol O-methyl transferase (COMT).[1][2] It was patented as an antiparkinsonian agent but was never marketed.[1]

See also[edit]


  1. ^ a b F.. Macdonald (1997). Dictionary of Pharmacological Agents. CRC Press. p. 1635. ISBN 978-0-412-46630-4. Retrieved 20 May 2012. 
  2. ^ Nissinen E, Lindén IB, Schultz E, Kaakkola S, Männistö PT, Pohto P (August 1988). "Inhibition of catechol-O-methyltransferase activity by two novel disubstituted catechols in the rat". European Journal of Pharmacology 153 (2-3): 263–9. doi:10.1016/0014-2999(88)90614-0. PMID 3181288.