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| doctoral_students = {{Plainlist|
| doctoral_students = {{Plainlist|
* Mario A. Fares<ref name=tree/>
* Mario A. Fares<ref name=tree/>
* [[d:Q30361498|Aoife McLysaght]]<ref name=tree>{{cite web|author=Anon|year=2017|url=https://academictree.org/compbio/tree.php?pid=64740|website=academictree.org|title=Kenneth H. Wolfe academic geneaology}} {{dead|date=July 2017}}</ref><ref name=aphd>{{cite thesis|degree=PhD|publisher=Trinity College, Dublin|title=Evolution of vertebrate genome organisation|first= Aoife |last=McLysaght|date=2002|url=https://search.proquest.com/docview/301572393|oclc=842498402}}</ref><ref name=alumni>{{cite web|archiveurl=https://web.archive.org/web/20170711122103/http://wolfe.ucd.ie/lab/yore.php|archivedate=2017-07-11|url=http://wolfe.ucd.ie/lab/yore.php|website=wolfe.ucd.ie|first=Ken|last=Wolfe|year=2017|title=Wolfe lab alumni}}</ref>
* [[d:Q30361498|Aoife McLysaght]]<ref name=tree>{{cite web|author=Anon |year=2017 |url=https://academictree.org/compbio/tree.php?pid=64740 |website=academictree.org |title=Kenneth H. Wolfe academic geneaology |deadurl=yes |archiveurl=https://web.archive.org/web/20170711135424/https://academictree.org/compbio/tree.php?pid=64740 |archivedate=2017-07-11 }} </ref><ref name=aphd>{{cite thesis|degree=PhD|publisher=Trinity College, Dublin|title=Evolution of vertebrate genome organisation|first= Aoife |last=McLysaght|date=2002|url=https://search.proquest.com/docview/301572393|oclc=842498402}}</ref><ref name=alumni>{{cite web|archiveurl=https://web.archive.org/web/20170711122103/http://wolfe.ucd.ie/lab/yore.php|archivedate=2017-07-11|url=http://wolfe.ucd.ie/lab/yore.php|website=wolfe.ucd.ie|first=Ken|last=Wolfe|year=2017|title=Wolfe lab alumni}}</ref>
* Estelle Proux-Wéra<ref name=tree/>
* Estelle Proux-Wéra<ref name=tree/>
* [[d:Q32937297|Cathal Seoighe]]<ref name=mathgene/><ref name=seo>{{cite thesis|degree=PhD|publisher=Trinity College, Dublin|title=Gene order evolution and genomic analysis of the model eukaryote, Saccharomyces cerevisiae, and other yeast species|first= Cathal|last=Seoighe|date=2000|url=https://search.proquest.com/docview/301607379|oclc=842501444}}</ref>}}
* [[d:Q32937297|Cathal Seoighe]]<ref name=mathgene/><ref name=seo>{{cite thesis|degree=PhD|publisher=Trinity College, Dublin|title=Gene order evolution and genomic analysis of the model eukaryote, Saccharomyces cerevisiae, and other yeast species|first= Cathal|last=Seoighe|date=2000|url=https://search.proquest.com/docview/301607379|oclc=842501444}}</ref>}}
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=== Awards and honours ===
=== Awards and honours ===
Wolfe was elected a [[List of Fellows of the Royal Society elected in 2017|Fellow of the Royal Society (FRS) in 2017]],<ref name=frs>{{cite web|url=https://royalsociety.org/people/kenneth-wolfe-13436/|title=Professor Kenneth Wolfe FRS|year=2017|website=royalsociety.org|publisher=[[Royal Society]]|location=London|author=Anon}} {{dead|date=July 2017}} One or more of the preceding sentences incorporates text from the royalsociety.org website where: {{quote|“All text published under the heading 'Biography' on Fellow profile pages is available under [[Creative Commons license|Creative Commons Attribution 4.0 International License]].” --{{Webarchive|url=http://web.archive.org/web/20161111170346/https://royalsociety.org/about-us/terms-conditions-policies/|title=Royal Society Terms, conditions and policies|date=2016-11-11}}}}</ref> a member of the [[Royal Irish Academy]] (MRIA) in 2000<ref name=ria /> and a member of the [[European Molecular Biology Organization|European Molecular Biology Organization (EMBO)]] in 2010.<ref name=membo>{{cite web|author=Anon|year=2010|url=http://people.embo.org/profile/kenneth-h-wolfe|location=Heidelberg|publisher=[[European Molecular Biology Organization]]|website=people.embo.org|title=EMBO member: Kenneth H. Wolfe}} {{dead|date=July 2017}}</ref> He previously{{when|date=July 2017}} served as president of the [[Society for Molecular Biology and Evolution|Society for Molecular Biology and Evolution (smbe.org)]].<ref name=frs/>
Wolfe was elected a [[List of Fellows of the Royal Society elected in 2017|Fellow of the Royal Society (FRS) in 2017]],<ref name=frs>{{cite web|url=https://royalsociety.org/people/kenneth-wolfe-13436/ |title=Professor Kenneth Wolfe FRS |year=2017 |website=royalsociety.org |publisher=[[Royal Society]] |location=London |author=Anon |deadurl=yes |archiveurl=https://web.archive.org/web/20170505140928/https://royalsociety.org/people/kenneth-wolfe-13436/ |archivedate=2017-05-05 }} One or more of the preceding sentences incorporates text from the royalsociety.org website where: {{quote|“All text published under the heading 'Biography' on Fellow profile pages is available under [[Creative Commons license|Creative Commons Attribution 4.0 International License]].” --{{cite web|url=https://royalsociety.org/about-us/terms-conditions-policies/ |title=Royal Society Terms, conditions and policies |accessdate=2016-03-09 |deadurl=bot: unknown |archiveurl=https://web.archive.org/web/20161111170346/https://royalsociety.org/about-us/terms-conditions-policies/ |archivedate=2016-11-11 }}}}</ref> a member of the [[Royal Irish Academy]] (MRIA) in 2000<ref name=ria /> and a member of the [[European Molecular Biology Organization|European Molecular Biology Organization (EMBO)]] in 2010.<ref name=membo>{{cite web|author=Anon |year=2010 |url=http://people.embo.org/profile/kenneth-h-wolfe |location=Heidelberg |publisher=[[European Molecular Biology Organization]] |website=people.embo.org |title=EMBO member: Kenneth H. Wolfe |deadurl=yes |archiveurl=https://web.archive.org/web/20170131223758/http://people.embo.org/profile/kenneth-h-wolfe |archivedate=2017-01-31 }} </ref> He previously{{when|date=July 2017}} served as president of the [[Society for Molecular Biology and Evolution|Society for Molecular Biology and Evolution (smbe.org)]].<ref name=frs/>


== References ==
== References ==

Revision as of 08:55, 14 July 2017

Ken Wolfe
Born
Kenneth H. Wolfe
Alma materTrinity College, Dublin (BA, PhD)
Awards
Scientific career
FieldsComparative genomics
Yeast genetics
Bioinformatics[4]
InstitutionsUniversity College Dublin
Indiana University Bloomington[5]
ThesisRates of nucleotide substitution in higher plants and mammals (1990)
Doctoral advisorPaul M. Sharp[6][7][8]
Other academic advisorsJeffrey D. Palmer[9]
Doctoral students
Websitewolfe.ucd.ie

Kenneth H. Wolfe FRS[1] MRIA[3] is Professor of Genomic Evolution at University College Dublin (UCD), Ireland.[13][3][14]

Education

Wolfe was educated at Trinity College, Dublin where he was awarded Bachelor of Arts degree in Genetics in 1986[5] followed by a PhD in 1990[8] for research investigating synonymous substitution in vascular plants and mammals supervised by Paul M. Sharp.[6][7][8][15]

Research and career

Wolfe's research focuses on comparative genomics, yeast genetics and bioinformatics.[4][16][17] Work in his laboratory investigates the evolution of eukaryotic genomes and chromosome organisation.[1] He is best known for his discovery that the genome of the yeast Saccharomyces cerevisiae underwent complete genome duplication about 100 million years ago,[18] an event that is now known to be the result of hybridization between two divergent species.[1] This finding reshaped our understanding both of yeast biology, and of mechanisms of genome evolution in eukaryotes.[1] His subsequent discoveries of similar ancient genome duplications (paleopolyploidy)[19] during human evolution, and in almost all families of flowering plants, led to the realisation that whole-genome duplication is widespread.[1] His group also studies the origin and evolution of mating systems in yeasts, and the process of mating-type switching in which one cell type can change into another by moving or replacing a section of chromosome.[1]

Prior to working at UCD, Wolfe was a postdoctoral researcher with Jeffrey D. Palmer[9] at Indiana University Bloomington before returning to Ireland in 1992.[5] As of 2017 his most highly cited peer reviewed papers[4][14][16] have been published in leading scientific journals including Nature,[18][20] Proceedings of the National Academy of Sciences of the United States of America,[21] The Plant Cell,[19][22] Genome Research[23] and Nature Reviews Genetics.[9]

Awards and honours

Wolfe was elected a Fellow of the Royal Society (FRS) in 2017,[1] a member of the Royal Irish Academy (MRIA) in 2000[3] and a member of the European Molecular Biology Organization (EMBO) in 2010.[2] He previously[when?] served as president of the Society for Molecular Biology and Evolution (smbe.org).[1]

References

  1. ^ a b c d e f g h i Anon (2017). "Professor Kenneth Wolfe FRS". royalsociety.org. London: Royal Society. Archived from the original on 2017-05-05. {{cite web}}: Unknown parameter |deadurl= ignored (|url-status= suggested) (help) One or more of the preceding sentences incorporates text from the royalsociety.org website where:

    “All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License.” --"Royal Society Terms, conditions and policies". Archived from the original on 2016-11-11. Retrieved 2016-03-09. {{cite web}}: Unknown parameter |deadurl= ignored (|url-status= suggested) (help)
  2. ^ a b Anon (2010). "EMBO member: Kenneth H. Wolfe". people.embo.org. Heidelberg: European Molecular Biology Organization. Archived from the original on 2017-01-31. {{cite web}}: Unknown parameter |deadurl= ignored (|url-status= suggested) (help)
  3. ^ a b c d Anon (2000). "Kenneth H. Wolfe FTCD". ria.ie. Dublin: Royal Irish Academy. [dead link]
  4. ^ a b c Kenneth H. Wolfe publications indexed by Google Scholar Edit this at Wikidata
  5. ^ a b c Ken Wolfe's ORCID 0000-0003-4992-4979
  6. ^ a b c d e Anon (2017). "Kenneth H. Wolfe academic geneaology". academictree.org. Archived from the original on 2017-07-11. {{cite web}}: Unknown parameter |deadurl= ignored (|url-status= suggested) (help)
  7. ^ a b c Kenneth H. Wolfe at the Mathematics Genealogy Project
  8. ^ a b c Wolfe, Kenneth H. (1990). Rates of nucleotide substitution in higher plants and mammals (PhD thesis). Trinity College, Dublin. OCLC 842511087.
  9. ^ a b c Wolfe, Kenneth H. (2001). "Yesterday's polyploids and the mystery of diploidization". Nature Reviews Genetics. 2 (5): 333–341. doi:10.1038/35072009. ISSN 1471-0056. PMID 11331899. (subscription required)
  10. ^ McLysaght, Aoife (2002). Evolution of vertebrate genome organisation (PhD thesis). Trinity College, Dublin. OCLC 842498402.
  11. ^ Wolfe, Ken (2017). "Wolfe lab alumni". wolfe.ucd.ie. Archived from the original on 2017-07-11.
  12. ^ Seoighe, Cathal (2000). Gene order evolution and genomic analysis of the model eukaryote, Saccharomyces cerevisiae, and other yeast species (PhD thesis). Trinity College, Dublin. OCLC 842501444.
  13. ^ UCD Professor Kenneth Wolfe elected Fellow of the Royal Society on YouTube, University College Dublin
  14. ^ a b Kenneth H. Wolfe publications from Europe PubMed Central
  15. ^ Sharp, Paul M.; Cowe, Elizabeth; Higgins, Desmond G.; Shields, Denis C.; Wolfe, Kenneth H.; Wright, Frank (1988). "Codon usage patterns in Escherichia coli, Bacillus subtilis, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Drosophila melanogaster and Homo sapiens; a review of the considerable within-species diversity". Nucleic Acids Research. 16 (17): 8207–8211. doi:10.1093/nar/16.17.8207. ISSN 0305-1048. PMC 338553. PMID 3138659.
  16. ^ a b Kenneth H. Wolfe publications indexed by the Scopus bibliographic database. (subscription required)
  17. ^ Sherlock, Gavin; Schröder, Markus S.; Martinez de San Vicente, Kontxi; Prandini, Tâmara H. R.; Hammel, Stephen; Higgins, Desmond G.; Bagagli, Eduardo; Wolfe, Kenneth H.; Butler, Geraldine (2016). "Multiple Origins of the Pathogenic Yeast Candida orthopsilosis by Separate Hybridizations between Two Parental Species". PLOS Genetics. 12 (11): e1006404. doi:10.1371/journal.pgen.1006404. ISSN 1553-7404. PMC 5091853. PMID 27806045.{{cite journal}}: CS1 maint: unflagged free DOI (link) Open access icon
  18. ^ a b Wolfe, Kenneth H.; Shields, Denis C. (1997). "Molecular evidence for an ancient duplication of the entire yeast genome". Nature. 387 (6634): 708–713. doi:10.1038/42711. ISSN 0028-0836. PMID 9192896. (subscription required)
  19. ^ a b Blanc, Guillaume; Wolfe, Kenneth H. (2004). "Widespread Paleopolyploidy in Model Plant Species Inferred from Age Distributions of Duplicate Genes". The Plant Cell. 16 (7): 1667–1678. doi:10.1105/tpc.021345. ISSN 1040-4651. PMC 514152. PMID 15208399.
  20. ^ Lander, E. S.; Linton, M.; Birren, B.; Nusbaum, C.; Zody, C.; Baldwin, J.; Devon, K.; Dewar, K.; Doyle, M.; Fitzhugh, W.; Funke, R.; Gage, D.; Harris, K.; Heaford, A.; Howland, J.; Kann, L.; Lehoczky, J.; Levine, R.; McEwan, P.; McKernan, K.; Meldrim, J.; Mesirov, J. P.; Miranda, C.; Morris, W.; Naylor, J.; Raymond, C.; Rosetti, M.; Santos, R.; Sheridan, A.; Sougnez, C. (2001). "Initial sequencing and analysis of the human genome". Nature. 409 (6822): 860–921. Bibcode:2001Natur.409..860L. doi:10.1038/35057062. hdl:2027.42/62798. ISSN 0028-0836. PMID 11237011. {{cite journal}}: Unknown parameter |displayauthors= ignored (|display-authors= suggested) (help)
  21. ^ Wolfe, K. H.; Li, W. H.; Sharp, P. M. (1987). "Rates of nucleotide substitution vary greatly among plant mitochondrial, chloroplast, and nuclear DNAs". Proceedings of the National Academy of Sciences. 84 (24): 9054–9058. doi:10.1073/pnas.84.24.9054. ISSN 0027-8424. PMC 299690. PMID 3480529.
  22. ^ Blanc, Guillaume; Wolfe, Kenneth H. (2004). "Functional Divergence of Duplicated Genes Formed by Polyploidy during Arabidopsis Evolution". The Plant Cell. 16 (7): 1679–1691. doi:10.1105/tpc.021410. ISSN 1040-4651. PMC 514153. PMID 15208398.
  23. ^ Blanc, G.; Hokamp, Karsten; Wolfe, Kenneth H. (2003). "A Recent Polyploidy Superimposed on Older Large-Scale Duplications in the Arabidopsis Genome". Genome Research. 13 (2): 137–144. doi:10.1101/gr.751803. ISSN 1088-9051. PMC 420368. PMID 12566392.
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