Radiography

For the medical specialty covering all imaging modes, see Radiology. For treatment using radiation, see Radiotherapy.

Radiography

Radiography of the knee in a modern X-ray machine.
System	Musculoskeletal
Subdivisions	Interventional, Nuclear, Oncological
Significant diseases	Cancer, Bone fractures
Significant tests	Screening tests, X-ray, CT, MRI, PET, Bone scan
Specialist	Radiographer

Radiography is an imaging technique using X-rays to view the internal structure of an object. To create the image, a beam of X-rays, a form of electromagnetic radiation, is produced by an X-ray generator and is projected toward the object. A certain amount of X-ray is absorbed by the object, dependent its density and composition. The X-rays that pass through the object are captured behind the object by a detector (either photographic film or a digital detector). The generation of flat two dimensional images by this technique is called projectional radiography. Computed tomography (CT scanning) is where multiple 2D images from different angles undergo computer processing to generate 3D representations.

Applications of radiography include medical (or "diagnostic") radiography and industrial radiography. Similar techniques are used in airport security (where "body scanners" generally use backscatter X-ray).

Equipment

A plain radiograph of the elbow.

Sources

Further information: X-ray generator

In medicine, projectional radiographs and computed tomography images are generally use X-rays created by X-ray generators, which generate X-rays from X-ray tubes.

A number of other sources of X-ray photons are possible, and may be used in industrial radiography or research; these include betatrons, and linear accelerators (linacs) and Synchrotrons. For gamma rays, radioactive sources such as ¹⁹²Ir, ⁶⁰Co or ¹³⁷Cs are used.

Grid

A Bucky-Potter grid may be placed between the patient and the detector to reduce the quantity of scattered x-rays that reach the detector. This improves the contrast resolution of the image, but also increases radiation exposure for the patient.

Detectors

Main article: X-ray detector

Detectors can be divided into two major categories: imaging detectors (such as photographic plates and X-ray film (photographic film), now mostly replaced by various digitizing devices like image plates or flat panel detectors) and dose measurement devices (such as ionization chambers, Geiger counters, and dosimeters used to measure the local radiation exposure, dose, and/or dose rate, for example, for verifying that radiation protection equipment and procedures are effective on an ongoing basis).

Image intensifiers and array detectors

Main article: X-ray image intensifier

As an alternative to X-ray detectors, Image intensifiers are analog devices that readily convert the acquired x-ray image into one visible on a video screen. This device is made of a vacuum tube with a wide input surface coated on the inside with caesium iodide (CsI). When hit by x-rays material phosphors which causes the photocathode adjacent to it to emit electrons. These electron are then focus using electron lenses inside the intensifier to an output screen coated with phosphorescent materials. The image from the output can then be recorded via a camera and displayed.

Digital devices known as array detectors are becoming more common in fluoroscopy. These devices are made of discrete pixelated detectors known as TFTs which can either work indirectly by using photo detectors that detect light emitted from a scintillator material such as CsI, or directly by capturing the electrons produced when the x-rays hit the detector. Direct detector do not tend to experience the blurring or spreading effect caused by phosphorescent scintillators of or film screens since the detectors are activated directly by x-ray photons.

Medical radiography

Radiography
ICD-9-CM	87, 88.0-88.6
MeSH	D011859
OPS-301 code	3-10...3-13, 3-20...3-26

Since the body is made up of various substances with differing densities, X-rays can be used to reveal the internal structure of the body on film by highlighting these differences using attenuation, or the absorption of X-ray photons by the denser substances (like calcium-rich bones). The discipline involving the study of anatomy through the use of radiographic films is known as radiographic anatomy. Medical radiography acquisition is generally carried out by radiographers, while image analysis is generally done by radiologists. Medical radiography includes a range of modalities producing many different types of image.

Projectional radiography

Main article: Projectional Radiography

Acquisition of projectional radiography, with an X-ray generator and a detector.

The creation of images by exposing an object to X-rays or other high-energy forms of electromagnetic radiation and capturing the resulting remnant beam (or "shadow") as a latent image is known as "projection radiography." The "shadow" may be converted to light using a fluorescent screen, which is then captured on photographic film, it may be captured by a phosphor screen to be "read" later by a laser (CR), or it may directly activate a matrix of solid-state detectors (DR—similar to a very large version of a CCD in a digital camera). Bone and some organs (such as lungs) especially lend themselves to projection radiography. It is a relatively low-cost investigation with a high diagnostic yield. The difference between soft and hard body parts stems mostly from the fact that carbon has a very low X-ray cross section compared to calcium.

Computed tomography

Main article: Computed tomography

Images generated from computed tomography, including a 3D rendered image at upper left.

Computed tomography or CT scan (previously known as CAT scan, the "A" standing for "axial") uses a high amount of ionizing radiation (in the form of X-rays) in conjunction with a computer to create images of both soft and hard tissues. These images look as though the patient was sliced like bread (thus, "tomography"-- "tomo" means "slice"). The exams are generally short, most lasting only as long as a breath-hold. Contrast agents are often used, depending on the tissues needing to be seen. Radiographers perform these examinations, sometimes in conjunction with a radiologist (for instance, when a radiologist performs a CT-guided biopsy).

Dual energy X-ray absorptiometry

Main article: Dual energy X-ray absorptiometry

DEXA, or bone densitometry, is used primarily for osteoporosis tests. It is not projection radiography, as the X-rays are emitted in 2 narrow beams that are scanned across the patient, 90 degrees from each other. Usually the hip (head of the femur), lower back (lumbar spine) or heel (calcaneum) are imaged, and the bone density (amount of calcium) is determined and given a number (a T-score). It is not used for bone imaging, as the image quality is not good enough to make an accurate diagnostic image for fractures, inflammation etc. It can also be used to measure total body fat, though this isn't common. The radiation dose received from DEXA scans is very low, much lower than projection radiography examinations.

Fluoroscopy

Main article: Fluoroscopy

Fluoroscopy is a term invented by Thomas Edison during his early X-ray studies. The name refers to the fluorescence he saw while looking at a glowing plate bombarded with X-rays.

The technique provides moving projection radiographs. Fluoroscopy is mainly performed to view movement (of tissue or a contrast agent), or to guide a medical intervention, such as angioplasty, pacemaker insertion, or joint repair/replacement. The latter are often carried out in the operating theatre, using a portable fluoroscopy machine called a C-arm. It can move around the surgery table and make digital images for the surgeon. Biplanar Fluoroscopy works the same as single plane fluoroscopy except displaying two planes at same the time. The ability to work in two planes is important for orthopedic and spinal surgery and can reduce operating times by eliminating re-positioning.

Angiography

Angiogram showing a transverse projection of the vertebro basilar and posterior cerebral circulation.

Main article: Angiography

Angiography is the use of fluoroscopy to view the cardiovascular system. An iodine-based contrast is injected into the bloodstream and watched as it travels around. Since liquid blood and the vessels are not very dense, a contrast with high density (like the large iodine atoms) is used to view the vessels under X-ray. Angiography is used to find aneurysms, leaks, blockages (thromboses), new vessel growth, and placement of catheters and stents. Balloon angioplasty is often done with angiography.

Contrast radiography

Main article: Radiocontrast agent

Contrast radiography uses a radiocontrast agent, a type of contrast medium, to make the structures of interest stand out visually from their background. Contrast agents are required in conventional angiography, and can be used in both projectional radiography and computed tomography (called "contrast CT").

Other medical imaging

Although not technically radiographic techniques due to not using X-rays, imaging modalities such as PET and MRI are sometimes grouped in radiography because the radiology department of hospitals handle all forms of imaging. Treatment using radiation is known as radiotherapy.

Industrial radiography

Main article: Industrial radiography

Industrial radiography is a method of non-destructive testing where many types of manufactured components can be examined to verify the internal structure and integrity of the specimen. Industrial Radiography can be performed utilizing either X-rays or gamma rays. Both are forms of electromagnetic radiation. The difference between various forms of electromagnetic energy is related to the wavelength. X and gamma rays have the shortest wavelength and this property leads to the ability to penetrate, travel through, and exit various materials such as carbon steel and other metals. Specific methods include industrial computed tomography.

Radiography may also be used in archeology, such as for these radiographs of the Darwinius fossil Ida.

Image quality

Sharpness of a radiographic image is strongly determined by the size of the x-ray source. This is determined by the area of the electron beam hitting the anode. A large photon source results in more blurring in the final image and is worsened by an increase in image formation distance. This blurring can be measured as a contribution to the modulation transfer function of the imaging system.

Shielding

Lead is the most common shield against X-rays because of its high density (11340 kg/m³), stopping power, ease of installation and low cost. The maximum range of a high-energy photon such as an X-ray in matter is infinite; at every point in the matter traversed by the photon, there is a probability of interaction. Thus there is a very small probability of no interaction over very large distances. The shielding of photon beam is therefore exponential (with an attenuation length being close to the radiation length of the material); doubling the thickness of shielding will square the shielding effect.

X-rays generated by peak voltages below	Minimum thickness of lead
75 kV	1.0 mm
100 kV	1.5 mm
125 kV	2.0 mm
150 kV	2.5 mm
175 kV	3.0 mm
200 kV	4.0 mm
225 kV	5.0 mm
300 kV	9.0 mm
400 kV	15.0 mm
500 kV	22.0 mm
600 kV	34.0 mm
900 kV	51.0 mm

The following table shows the recommended thickness of lead shielding in function of X-ray energy, from the Recommendations by the Second International Congress of Radiology.

History

Further information: X-ray § History

Taking an X-ray image with early Crookes tube apparatus, late 1800s.

Radiography's origins and fluoroscopy's origins can both be traced to November 8, 1895, when German physics professor Wilhelm Conrad Röntgen discovered the X-ray and noted that, while it could pass through human tissue, it could not pass through bone or metal. Röntgen referred to the radiation as "X", to indicate that it was an unknown type of radiation. He received the first Nobel Prize in Physics for his discovery.

There are conflicting accounts of his discovery because Röntgen had his lab notes burned after his death, but this is a likely reconstruction by his biographers: Röntgen was investigating cathode rays using a fluorescent screen painted with barium platinocyanide and a Crookes tube which he had wrapped in black cardboard to shield its fluorescent glow. He noticed a faint green glow from the screen, about 1 metre away. Röntgen realized some invisible rays coming from the tube were passing through the cardboard to make the screen glow: they were passing through an opaque object to affect the film behind it.

The first radiograph

Röntgen discovered X-rays' medical use when he made a picture of his wife's hand on a photographic plate formed due to X-rays. The photograph of his wife's hand was the first ever photograph of a human body part using X-rays. When she saw the picture, she said, "I have seen my death."

The first use of X-rays under clinical conditions was by John Hall-Edwards in Birmingham, England on 11 January 1896, when he radiographed a needle stuck in the hand of an associate. On 14 February 1896, Hall-Edwards also became the first to use X-rays in a surgical operation.

The United States saw its first medical X-ray obtained using a discharge tube of Ivan Pulyui's design. In January 1896, on reading of Röntgen's discovery, Frank Austin of Dartmouth College tested all of the discharge tubes in the physics laboratory and found that only the Pulyui tube produced X-rays. This was a result of Pulyui's inclusion of an oblique "target" of mica, used for holding samples of fluorescent material, within the tube. On 3 February 1896 Gilman Frost, professor of medicine at the college, and his brother Edwin Frost, professor of physics, exposed the wrist of Eddie McCarthy, whom Gilman had treated some weeks earlier for a fracture, to the X-rays and collected the resulting image of the broken bone on gelatin photographic plates obtained from Howard Langill, a local photographer also interested in Röntgen's work.

X-rays were put to diagnostic use very early; for example, Alan Archibald Campbell-Swinton opened a radiographic laboratory in the United Kingdom in 1896, before the dangers of ionizing radiation were discovered. Indeed, Marie Curie pushed for radiography to be used to treat wounded soldiers in World War I. Initially, many kinds of staff conducted radiography in hospitals, including Physicists, Photographers, Physicians, Nurses, and Engineers. The medical speciality of radiology grew up over many years around the new technology. When new diagnostic tests were developed, it was natural for the Radiographers to be trained in and to adopt this new technology. Radiographers now perform fluoroscopy, computed tomography, mammography, ultrasound, nuclear medicine and magnetic resonance imaging as well. Although a nonspecialist dictionary might define radiography quite narrowly as "taking X-ray images", this has long been only part of the work of "X-ray Departments", Radiographers, and Radiologists. Initially, radiographs were known as roentgenograms, while Skiagrapher (from the Ancient Greek words for "shadow" and "writer") was used until about 1918 to mean Radiographer.

See also

• Background radiation
• Imaging science
• Computer-aided diagnosis
• Medical imaging in pregnancy
• Radiation
• Radiation contamination
• List of civilian radiation accidents
• Radiographer
• Thermography

External links

• MedPix Medical Image Database
• Video on X-ray inspection and industrial computed tomography, Karlsruhe University of Applied Sciences
• NIST's XAAMDI: X-Ray Attenuation and Absorption for Materials of Dosimetric Interest Database
• NIST's XCOM: Photon Cross Sections Database
• NIST's FAST: Attenuation and Scattering Tables
• A lost industrial radiography source event
• RadiologyInfo - The radiology information resource for patients: Radiography (X-rays)

Further reading

• Carestream. (http://www.kodak.com/global/en/health/productsByType/index.jhtml?pq-path=2/521/2970)
• A review on the subject of medical X-ray examinations and metal based contrast agents, by Shi-Bao Yu and Alan D. Watson, Chemical Reviews, 1999, volume 99, pages 2353–2378
• Composite Materials for Aircraft Structures by Alan Baker, Stuart Dutton (Ed.), AIAA (American Institute of Aeronautics & Ast) ISBN 1-56347-540-5
• Radiation Safety in Industrial Radiography, Specific Safety Guide No. SSG-11, International Atomic Energy Agency, Vienna, 2011.
• Howard H. Seliger: Wilhelm Conrad Röntgen and the Glimmer of Light. Physics Today, November 1995, 25-31, http://hdl.handle.net/10013/epic.43596.d001
• Shroy, Jr., Robert E. (1995). "X-Ray equipment". In Bronzino, J.D. (ed.). The Biomedical Engineering handbook. CRC Press and IEEE Press. pp. 953–960. ISBN 0-8493-8346-3.
• Bushberg, Jerrold T.; Seibert, J. Anthony; Leidholdt Jr., Edwin M.; Boone, John M. (2001). The Essential Physics of Medical Imaging (2nd ed.). Lippincott Williams & Wilkins. ISBN 978-0-683-30118-2.
• Herman, Gabor T. (2009). Fundamentals of Computerized Tomography: Image Reconstruction from Projections (2nd ed.). Springer. ISBN 978-1-85233-617-2.
• Kodak. (http://www.kodak.com/global/en/health/productsByType/index.jhtml?pq-path=2/521/2970)
• Agfa. (http://www.piribo.com/publications/medical_devices/mdc/agfa_medical.html)
• Yu, Shi-Bao; Alan D. Watson (1999). "A review on the subject of medical X-ray examinations and metal based contrast agents". Chemical Reviews. 99 (9): 2353–2378. doi:10.1021/cr980441p. PMID 11749484.
• Baker, Alan; Stuart Dutton (Ed.) (2004). Composite Materials for Aircraft Structures. American Institute of Aeronautics & Ast. ISBN 1-56347-540-5.