Disulfoglucosamine-6-sulfatase
Appearance
disulfoglucosamine-6-sulfatase | |||||||||
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Identifiers | |||||||||
EC no. | 3.1.6.11 | ||||||||
CAS no. | 37288-32-7 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a disulfoglucosamine-6-sulfatase (EC 3.1.6.11) is an enzyme that catalyzes the chemical reaction
- N,6-O-disulfo-D-glucosamine + H2O N-sulfo-D-glucosamine + sulfate
Thus, the two substrates of this enzyme are N,6-O-disulfo-D-glucosamine and H2O, whereas its two products are N-sulfo-D-glucosamine and sulfate.
This enzyme belongs to the family of hydrolases, specifically those acting on sulfuric ester bonds. The systematic name of this enzyme class is N,6-O-disulfo-D-glucosamine 6-sulfohydrolase. Other names in common use include N-sulfoglucosamine-6-sulfatase, and 6,N-disulfoglucosamine 6-O-sulfohydrolase.
References
- Dietrich CP (January 1969). "Enzymic degradation of heparin. A sulphamidase and a sulphoesterase from Flavobacterium heparinum". The Biochemical Journal. 111 (1): 91–5. PMC 1187498. PMID 5775690.