S-succinylglutathione hydrolase
| S-succinylglutathione hydrolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.2.13 | ||||||||
| CAS no. | 50812-22-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a S-succinylglutathione hydrolase (EC 3.1.2.13) is an enzyme that catalyzes the chemical reaction
- S-succinylglutathione + H2O glutathione + succinate
Thus, the two substrates of this enzyme are S-succinylglutathione and H2O, whereas its two products are glutathione and succinate.
This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is S-succinylglutathione hydrolase.
References
- Uotila L (September 1973). "Preparation and assay of glutathione thiol esters. Survey of human liver glutathione thiol esterases". Biochemistry. 12 (20): 3938–43. doi:10.1021/bi00744a024. PMID 4200890.
- Uotila L (August 1979). "Purification and properties of S-succinylglutathione hydrolase from human liver". The Journal of Biological Chemistry. 254 (15): 7024–9. PMID 457667.
