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Exodeoxyribonuclease (phage SP3-induced)

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Exodeoxyribonuclease (phage SP3-induced)
Identifiers
EC no.3.1.11.4
CAS no.37288-30-5
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Exodeoxyribonuclease (phage SP3-induced) (EC 3.1.11.4, phage SP3 DNase, DNA 5'-dinucleotidohydrolase, deoxyribonucleate 5'-dinucleotidase, deoxyribonucleic 5'-dinucleotidohydrolase, bacteriophage SP3 deoxyribonuclease) is an enzyme.[1] This enzyme catalyses the following chemical reaction

Exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 5'-phosphates

Preference for single-stranded DNA.

References

  1. ^ Trilling DM, Aposhian HV (May 1968). "Sequential cleavage of dinucleotides from DNA by phage Sp3 DNAse". Proceedings of the National Academy of Sciences of the United States of America. 60 (1): 214–21. Bibcode:1968PNAS...60..214T. doi:10.1073/pnas.60.1.214. PMC 539104. PMID 4968633.