Amanin

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Amanin
Amanin.png
Identifiers
3D model (Jmol)
ChemSpider
Properties
C39H53N9O14S
Molar mass 903.96 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Amanin is a cyclic peptide. It is one of the amatoxins, all of which are found in several members of the Amanita genus of mushrooms.

Toxicology[edit]

Like other amatoxins, amanin is an inhibitor of RNA polymerase II. Upon ingestion, it binds to the RNA polymerase II enzyme which completely prevents mRNA synthesis, effectively causing cytolysis of hepatocytes (liver cells) and kidney cells.[1]

See also[edit]

References[edit]