Brinnington is a north-eastern suburb of Stockport, Greater Manchester, England, on a bluff above a bend in the Tame Valley. It was reported to have the highest prevalence of depression in England.
Brinnington was open farm land before the local authority housing developments of the 1950s and 1960s. To the west of Brinnington is Reddish Vale, a country park popular with families to go for a walk and explore the ponds and brick viaducts; under the arches there is a sharp bend in the river and sand has been deposited giving the effect of a miniature beach.
The area consists mainly of council owned dwellings including high rise flats. Brinnington has high crime levels and long-term unemployment at 20%. Two streets, Northumberland Road and Brinnington Road, were named by police as two of the three worst roads in Stockport in 2010.
The area is being regenerated, including the demolition of the Top Shops in 2007, which were replaced by new shops, 53 shared ownership houses and First House. In 2009, 17 new homes were built at Lantern Close, a new road named after the annual lantern parade in the area.
The original proposed Manchester congestion charge would have charged motorists for crossing the M60 motorway, and protests from local residents led to a change in the proposed boundaries, excluding Brinnington from the charge zone. It is sandwiched between the M60 motorway and Reddish Vale Country park, and this and congested road constrain buses creating a sense of isolation. 
There are three primary schools, St. Paul's, St. Bernadette's (Roman Catholic) and Westmorland, the last being an amalgamation of the former Brindale, Maycroft and Tame Valley Primary Schools.
A survey was done by a local GP, to investigate why the depression rate in Brinnington was 23.6%, compared with an average of 9.8% in the rest of England. His records concurred. In his last 123 patients, 24% were seeking help with depression, while a further 28% were under treatment and 16% had been.
- Pidd, Helen (6 May 2019). "Is this the most depressed place in England?". The Guardian. Retrieved 16 January 2020.
- Latham, Cheryl (14 April 2010). "'Worst' roads in Stockport named by police". Stockport Express. M.E.N. Media.
- picture of Brinnington
- http://www.bfaw.co.uk/viewItem.asp?portfolioID=24&areaID=8&selectedImage=259[permanent dead link]
- Rathbone, Gemma (16 May 2007). "Brinnington's First House is first rate centre". Stockport Express. M.E.N. Media.
- "Archived copy". Archived from the original on 6 April 2012. Retrieved 18 April 2010.CS1 maint: archived copy as title (link)
- "Changes to city's congestion plan". BBC News. 27 October 2008.
- Transco plc v Stockport Metropolitan BC  UKHL 61