CAPN5

CAPN5
Identifiers
Aliases	CAPN5, ADNIV, HTRA3, VRNI, nCL-3, calpain 5
External IDs	OMIM: 602537; MGI: 1100859; HomoloGene: 31212; GeneCards: CAPN5; OMA:CAPN5 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	77,126,155 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	98,178,274 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; rectum; ; gallbladder; ; right lobe of liver; ; stromal cell of endometrium; ; mucosa of esophagus; ; duodenum; ; body of stomach; ; mucosa of ileum; ; palpebral conjunctiva;
	Top expressed in
	transitional epithelium of urinary bladder; ; lumbar spinal ganglion; ; pyloric antrum; ; epithelium of stomach; ; conjunctival fornix; ; mucous cell of stomach; ; perirhinal cortex; ; fetal liver hematopoietic progenitor cell; ; corneal stroma; ; entorhinal cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	peptidase activity; cysteine-type peptidase activity; hydrolase activity; calcium-dependent cysteine-type endopeptidase activity;
Cellular component	cell surface; extracellular exosome; intracellular anatomical structure; focal adhesion; cytoplasm;
Biological process	signal transduction; proteolysis;
	Sources:Amigo / QuickGO
Orthologs
	726
	12337
	ENSG00000149260
	ENSMUSG00000035547
	O15484
	O08688
	NM_004055
	NM_001301250; NM_007602
	NP_004046
	NP_001288179; NP_031628
	Wikidata
View/Edit Human	View/Edit Mouse

Calpain-5 is a protein that in humans is encoded by the CAPN5 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000149260 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000035547 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Matena K, Boehm T, Dear N (Apr 1998). "Genomic organization of mouse Capn5 and Capn6 genes confirms that they are a distinct calpain subfamily". Genomics. 48 (1): 117–20. doi:10.1006/geno.1997.5133. PMID 9503024.
^ Mugita N, Kimura Y, Ogawa M, Saya H, Nakao M (Dec 1997). "Identification of a novel, tissue-specific calpain htra-3; a human homologue of the Caenorhabditis elegans sex determination gene". Biochem Biophys Res Commun. 239 (3): 845–50. doi:10.1006/bbrc.1997.7571. PMID 9367857.
^ "Entrez Gene: CAPN5 calpain 5".

This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by expanding it.

v t e Proteases: cysteine proteases (EC 3.4.22)
Caspase	Caspase 1 Caspase 2 Caspase 3 Caspase 4 Caspase 5 Caspase 6 Caspase 7 Caspase 8 Caspase 9 Caspase 10 Caspase 12 Caspase 13 Caspase 14
Fruit-derived	Papain Ficain Bromelain Actinidain
Calpain	CAPN1 CAPN2 CAPN3 CAPN5 CAPN6 CAPN7 CAPN8 CAPN9 CAPN10 CAPN11 CAPN12 CAPN13 CAPN14 CAPNS1 CAPNS2
Cathepsin	B C F H K L1/L2 O S W Z
Other	Clostripain Cancer procoagulant Separase Autophagin Cruzipain 3C-like protease Gingipain R Gingipain K