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Deoxyadenosine triphosphate

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This is an old revision of this page, as edited by 192.114.91.230 (talk) at 10:34, 6 February 2018 (I changed nucleoside to nucleotide, since clearly deoxyadenosine triphosphate has phosphate groups attached, and that classifies it as a nucleotide). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Deoxyadenosine triphosphate
Skeletal formula of deoxyadenosine triphosphate
Ball-and-stick model of the deoxyadenosine triphosphate anion
Names
IUPAC name
[[(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Other names
dATP, 2'-deoxyadenosine triphosphate
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.016.058 Edit this at Wikidata
  • InChI=1S/C10H16N5O12P3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(25-7)2-24-29(20,21)27-30(22,23)26-28(17,18)19/h3-7,16H,1-2H2,(H,20,21)(H,22,23)(H2,11,12,13)(H2,17,18,19)/t5-,6+,7+/m0/s1 checkY=  checkY
    Key: SUYVUBYJARFZHO-RRKCRQDMSA-N checkY=  checkY
  • InChI=1/C10H16N5O12P3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(25-7)2-24-29(20,21)27-30(22,23)26-28(17,18)19/h3-7,16H,1-2H2,(H,20,21)(H,22,23)(H2,11,12,13)(H2,17,18,19)/t5-,6+,7+/m0/s1
    Key: SUYVUBYJARFZHO-RRKCRQDMBD
  • O=P(O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]3O[C@@H](n2cnc1c(ncnc12)N)C[C@@H]3O
Properties
C10H16N5O12P3
Molar mass 491.181623
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)

Deoxyadenosine triphosphate (dATP) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA Polymerase.[1] Findings have also suggested that dATP can act as an energy-transferring molecule to maintain cell viability.[2]

See also

References

  1. ^ Romaniuk, P. J.; Eckstein, F. (1982-07-10). "A study of the mechanism of T4 DNA polymerase with diastereomeric phosphorothioate analogues of deoxyadenosine triphosphate". The Journal of Biological Chemistry. 257 (13): 7684–7688. ISSN 0021-9258. PMID 7045112.
  2. ^ Nakashima, K.; Nakashima, H.; Shimoyama, M. (1991-09-24). "Deoxyadenosine triphosphate acting as an energy-transferring molecule in adenosine deaminase inhibited human erythrocytes". Biochimica et Biophysica Acta. 1094 (3): 257–262. doi:10.1016/0167-4889(91)90084-b. ISSN 0006-3002. PMID 1911876.


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