Dolichylphosphate-mannose phosphodiesterase
| dolichylphosphate-mannose phosphodiesterase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.4.49 | ||||||||
| CAS no. | 111839-07-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a dolichylphosphate-mannose phosphodiesterase (EC 3.1.4.49) is an enzyme that catalyzes the chemical reaction
- dolichyl beta-D-mannosyl phosphate + H2O dolichyl phosphate + D-mannose
Thus, the two substrates of this enzyme are dolichyl beta-D-mannosyl phosphate and H2O, whereas its two products are dolichyl phosphate and D-mannose.
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name of this enzyme class is dolichyl-beta-D-mannosyl-phosphate dolichylphosphohydrolase. This enzyme is also called mannosylphosphodolichol phosphodiesterase.
References
- Tomita Y, Motokawa Y (1987). "Characterization and partial purification of a novel mannosylphosphodolichol phosphodiesterase from chicken liver microsomes". Eur. J. Biochem. 170 (1–2): 363–8. doi:10.1111/j.1432-1033.1987.tb13708.x. PMID 2826159.