Norfloxacin

Norfloxacin
Clinical data
ATC code	J01MA06 (WHO) S01AX12 (WHO);
Pharmacokinetic data
Elimination half-life	3 to 4 hours
Identifiers
	IUPAC name 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1H-quinoline-; 3-carboxylic acid;
CAS Number	70458-96-7;
PubChem CID	4539;
DrugBank	APRD00469;
CompTox Dashboard (EPA)	DTXSID7037680 ;
ECHA InfoCard	100.067.810
Chemical and physical data
Formula	C16H18FN3O3
Molar mass	319.331 g/mol g·mol−1

Norfloxacin is an oral broad-spectrum fluoroquinolone antibacterial agent used in the treatment of urinary tract infections. It is also sometimes used to treat stomach infections.

Mechanism of action

The mechanism of action of norfloxacin involves inhibition of the A subunit of bacterial DNA gyrase, an enzyme which is essential for DNA replication.^[1] from: Prof. SANDIP J PATEL, KOT, India

References

^ Goldstein E (1987). "Norfloxacin, a fluoroquinolone antibacterial agent. Classification, mechanism of action, and in vitro activity". Am J Med. 82 (6B): 3–17. doi:10.1016/0002-9343(87)90612-7. PMID 3111257.

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[1] Goldstein E (1987). "Norfloxacin, a fluoroquinolone antibacterial agent. Classification, mechanism of action, and in vitro activity". Am J Med. 82 (6B): 3–17. doi:10.1016/0002-9343(87)90612-7. PMID 3111257.

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