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Lomefloxacin ball-and-stick.png
Clinical data
Trade names Maxaquin
AHFS/Drugs.com Consumer Drug Information
MedlinePlus a600002
ATC code J01MA07 (WHO) S01AE04 (WHO)
Pharmacokinetic data
Protein binding 10%
Biological half-life 8 hours
CAS Number 98079-51-7 YesY
PubChem (CID) 3948
DrugBank DB00978 YesY
ChemSpider 3811 YesY
KEGG D02318 YesY
ChEBI CHEBI:116278 YesY
ECHA InfoCard 100.117.399
Chemical and physical data
Formula C17H19F2N3O3
Molar mass 351.348 g/mol
3D model (Jmol) Interactive image

Lomefloxacin hydrochloride (sold under the following brand names in English speaking countries Maxaquin, Okacyn, Uniquin) is a fluoroquinolone antibiotic used to treat bacterial infections including bronchitis and urinary tract infections. It is also used to prevent urinary tract infections prior to surgery. Lomefloxacin is associated with phototoxicity and central nervous system adverse effects.[1]

October 2008 the FDA added the following black box warning to the product insert for Maxaquin: Lomefloxacin is unique in that it forms a magnesium chelate with itself. The chelate is formed between the 2-carbonyl group of two separate lomefloxacin molecules.

See also[edit]


  1. ^ Rubinstein, E. (2001). "History of quinolones and their side effects.". Chemotherapy. 47 (Suppl 3): 3–8; discussion 44–8. doi:10.1159/000057838. PMID 11549783.