Ornidazole

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Not to be confused with ronidazole.
Ornidazole
Ornidazole.svg
Systematic (IUPAC) name
1-chloro-3-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol
Clinical data
Trade names Xynor
AHFS/Drugs.com International Drug Names
Routes of
administration
Oral
Pharmacokinetic data
Metabolism Metabolised via the liver, excreted in the Urine and Feces
Excretion 85% of single oral dose is eliminated with 5 days - Urine (63%) and Feces (22%)
Identifiers
CAS Registry Number 16773-42-5 YesY
ATC code G01AF06 J01XD03 P01AB03 QP51AA03
PubChem CID: 28061
ChemSpider 26102 YesY
UNII 62XCK0G93T YesY
KEGG D05274 YesY
ChEBI CHEBI:75176 N
ChEMBL CHEMBL1449676 N
Chemical data
Formula C7H10ClN3O3
Molecular mass 219.625
 N (what is this?)  (verify)

Ornidazole is a drug that cures some protozoan infections.

It has been investigated for use in Crohn's disease after bowel resection.[1] ATC (Anatomical Therapeutic Chemical Classification)

[2]2International : Avrazor, Biteral, Borneral, Dazolic, Invigan, Mebaxol, Oniz, Orni, Ornid, Ornidazol Biocrom, Ornidazol Gemepe, Ornidazol Richet, Ornidazole Serb, Ornidazol-Vero, Ornidone, Ornil, Ornisid, Ornitop, Robic, Tiberal, Tibéral, Xynor Why it is prescribed (Indications) :

This medication is an antiamoebic agent, prescribed for amoebic dysentery. When it is not to be taken (Contraindications):

Hypersensitivity.


Pregnancy Category :


A

B

C

D

X


Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken :

PO: Adult- The recommended dose range is 0.5gm to 1.5gm daily for 1 to 7 days.


How it should be taken :

It comes as a tablet to take by mouth as directed by your physician. Warnings and Precautions : Caution should be exercised in patients with history of epilepsy, multiple sclerosis, liver or kidney disease, during pregnancy and breastfeeding.

It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication. 

Side Effects :

 Central Nervous System- Drowsiness, dizziness, headache, tremor, rigidity, poor coordination, epilepsy, tiredness, temporary loss of consciousness and fainting. 
 Miscellaneous- Nausea, vomiting, taste disturbances, liver impairment, skin reactions like rash, itching and inflammation. 

Other Precautions : Avoid excess dosage. Storage Conditions : Store it at room temperature, and keep away from children.2 [3]


References[edit]