Flutrimazole

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Flutrimazole
Flutrimazole.svg
Clinical data
AHFS/Drugs.com International Drug Names
ATC code
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
Chemical and physical data
Formula C22H16F2N2
Molar mass 346.373 g/mol
3D model (Jmol)
Chirality Racemic mixture
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Flutrimazole is a wide-spectrum antifungal drug. It is used for the topical treatment of superficial mycoses of the skin. Flutrimazole is an imidazole derivative. Its antifungal activity has been demonstrated in in vivo and in vitro studies to be comparable to that of clotrimazole and higher than bifonazole.[1]

Mechanism of action[edit]

It interferes with the synthesis of ergosterol by inhibiting the activity of the enzyme lanosterol 14 α-demethylase.

See also[edit]

References[edit]

The Merck Index, 12th Edition. 4247

  1. ^ Alomar, A; Videla, S; Delgadillo, J; Gich, I; Izquierdo, I; Forn, J (1995). "Flutrimazole 1% Dermal Cream in the Treatment of Dermatomycoses: a Multicentre, Double-Blind, Randomized, Comparative Clinical Trial with Bifonazole 1% Cream. Efficacy of Flutrimazole 1% Dermal Cream in Dermatomycoses. Catalan Flutrimazole Study Group". Dermatology (Basel, Switzerland). 190 (4): 295–300. PMID 7655109.