|Jmol interactive 3D||Image|
|Molar mass||248.28 g/mol|
|Melting point||131 °C (268 °F; 404 K)|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|what is ?)(|
Sudan I (also commonly known as CI Solvent Yellow 14 and Solvent Orange R), is an organic compound, typically classified as an azo dye. It is an intensely orange-red solid that is added to colourise waxes, oils, petrol, solvents and polishes. Sudan I has also been adopted for colouring various foodstuffs, especially curry powder and chili powder, although the use of Sudan I in foods is now banned in many countries, because Sudan I, Sudan III, and Sudan IV have been classified as category 3 carcinogens (not classifiable as to its carcinogenicity to humans) by the International Agency for Research on Cancer. Sudan I is still used in some orange-coloured smoke formulations and as a colouring for cotton refuse used in chemistry experiments.
Sudan I is genotoxic. It is also carcinogenic in rats. Comparisons between experimental animals and human Cytochrome P450 (CYP) strongly suggest animal carcinogenicity data can be extrapolated to humans.
Sudan I is also present as an impurity in Sunset Yellow, which is its disulfonated water-soluble version.
In February 2005, Sudan I gained attention, particularly in the United Kingdom. A Worcestershire sauce produced by Premier Foods was found to be contaminated with Sudan I. The origin was traced to adulterated chili powder. The contamination was discovered by the Food Standards Agency.
Synonyms and brand names
- Refat NA, Ibrahim ZS, Moustafa GG, Sakamoto KQ, Ishizuka M, Fujita S (2008). "The induction of cytochrome P450 1A1 by sudan dyes". J. Biochem. Mol. Toxicol. 22 (2): 77–84. doi:10.1002/jbt.20220. PMID 18418879.
- Larsen, John Chr. "Legal and illegal colors" Trends in Food Science & Technology (2008), 19(Suppl. 1), S60-S65. doi:10.1016/j.tifs.2008.07.008
- Stiborová M, Martínek V, Rýdlová H, Hodek P, Frei E (October 2002). "Sudan I is a potential carcinogen for humans: evidence for its metabolic activation and detoxication by human recombinant cytochrome P450 1A1 and liver microsomes". Cancer Res. 62 (20): 5678–84. PMID 12384524.
- "Sudan outraged at namesake dye". BBC. 2005-03-04. Retrieved 2008-09-08.