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Actinomycin lactonase

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actinomycin lactonase
Identifiers
EC no.3.1.1.39
CAS no.37288-09-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

The enzyme actinomycin lactonase (EC 3.1.1.39) catalyzes the reaction

actinomycin + H2O actinomycinic monolactone

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is actinomycin lactonohydrolase.

References

[edit]
  • Hou CT, Perlman D (1970). "Microbial transformations of peptide antibiotics. V. Purification and properties of the actinomycin lactonase from Actinoplanes missouriensis". J. Biol. Chem. 245 (6): 1289–95. PMID 4191854.