The following are the football (soccer) events of the year 1965 throughout the world.
- Copa Libertadores 1965: Won by Independiente after defeating Peñarol on an aggregate score of 4-1.
- February 6:Retirement of Sir Stanley Matthews from professional football, five days after his fiftieth birthday.
- Substitutions allowed: The Football League voted 39 to 10 in favour of allowing clubs to introduce a substitute for an injured player at any time during a league match.
- FC Twente (Enschede, the Netherlands) was founded
Winners club national championship
- January 13 – Bennett Masinga, South African international footballer (died 2013)
- February 4 – John van Loen, Dutch footballer and assistant-coach
- February 15 – Gustavo Quinteros, Bolivian footballer and manager
- March 8 – Juan Hernández Ramírez, Mexican footballer
- May 17 – Massimo Crippa, Italian footballer
- June 12 – Carlos Luis Morales, Ecuadorian goalkeeper
- July 27 – José Luis Chilavert, Paraguayan goalkeeper
- July 30 – Leonel Álvarez, Colombian footballer
- August 31 – Ricardo Gónzalez, Chilean footballer
- September 7 – Darko Pančev, Macedonian footballer
- September 24 – Roberto Siboldi, Uruguayan footballer
- October 6 – Jürgen Kohler, German international footballer and manager
- November 16 – Mika Aaltonen, Finnish footballer
- November 24 – Tom Boyd, Scottish footballer
- November 25 – Mauro Blanco, Bolivian footballer
- December 10 – José Aurelio Gay, Spanish football player and manager