Amanullinic acid
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Other names
1-L-Aspartic acid-3-isoleucine-alpha-amanitin
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Identifiers | |
3D model (JSmol)
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ChemSpider | |
PubChem CID
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Properties | |
C39H53N9O13S | |
Molar mass | 887.96 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Amanullinic acid is a cyclic nonribosomal peptide. It is an amatoxin, all of which are found in several members of the Amanita genus of mushrooms. The oral LD50 of amanullinic acid is approximately 0.1 mg/kg in mice.[1]
Toxicology
Like other amatoxins, amanullinic acid is an inhibitor of RNA polymerase II.
See also
References
- ^ T. Wieland and Faulstich H. (1978). "Amatoxins, Phallotoxins, Phallolysin, and Antamanide: the Biologically Active Components of Poisonous Amanita Mushrooms". CRC Critical Reviews in Biochemistry. 5 (3): 185–260. doi:10.3109/10409237809149870. PMID 363352.