Michael N. Hall

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Michael N. Hall
Hall in 2014
NationalitySwiss, American
Alma materUniversity of North Carolina at Chapel Hill (B.S., 1976)
Harvard University (Ph.D., 1981)
Known formTOR
Awards
Scientific career
FieldsMolecular biology
InstitutionsUniversity of North Carolina at Chapel Hill
Harvard University
Institut Pasteur
University of California, San Francisco
Biozentrum University of Basel

Michael Nip Hall (born 1953[1]) is an American-Swiss molecular biologist and professor at the Biozentrum University of Basel, Switzerland.

Life

Hall grew up in South America (Venezuela, Peru). He earned a Bachelor of Science in Zoology from the University of North Carolina at Chapel Hill in 1976, and a PhD in Molecular Genetics from Harvard University in 1981. Hall was a postdoctoral fellow at the Institut Pasteur in Paris and at the University of California, San Francisco. He was appointed an assistant professor at the Biozentrum of the University of Basel in 1987, and became a full professor in 1992. From 1995 to 1998 and from 2002 to 2009 he was head of the Division of Biochemistry, and from 2002 until 2009 was Deputy Director of the Biozentrum.[2]

Work

Hall is a pioneer in the fields of TOR signaling and cell growth control.[3] In 1991, Michael N. Hall discovered a protein, which regulates cell growth, cell size and cell division in yeast cells.[4] Since the function of this protein is inhibited by the substance rapamycin, Hall gave the growth regulator the name "Target of Rapamycin" or for short "TOR". TOR is a conserved protein kinase activated by growth factors, nutrients, and insulin. It is a central controller of cell growth and metabolism. TOR plays a key role in aging and the development of diseases such as cancer, obesity, Diabetes mellitus, and cardiovascular disease. Insights into TOR signaling pathways have been applied for new therapeutic strategies.[5][6] In 2017, Hall received the Albert Lasker Basic Medical Research Award.[7]

Awards and honors

References

  1. ^ a b "Professor Michael N. HALL | Jeantet". October 1, 2017.
  2. ^ Curriculum Vitae Biozentrum.unibas.ch Retrieved December 13, 2021
  3. ^ Short Biography Archived October 18, 2014, at the Wayback Machine, De Duve Institute Retrieved October 22, 2013
  4. ^ Heitman, J.; Movva, N.; Hall, M. (August 1991). "Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast". Science. 253 (5022): 905–9. Bibcode:1991Sci...253..905H. doi:10.1126/science.1715094. PMID 1715094. S2CID 9937225.
  5. ^ Introduction Michael N. Hall Archived October 16, 2014, at the Wayback Machine bioss.uni-freiburg.de Retrieved October 22, 2013
  6. ^ Unveiling the Secret of Cell Growth Karger.com Retrieved September 16, 2015
  7. ^ Foundation, Lasker. "Nutrient-activated TOR proteins that regulate cell growth | The Lasker Foundation". The Lasker Foundation. Retrieved March 5, 2018.
  8. ^ European Molecular Biology Organization Membership Guide 2012 Retrieved October 22, 2013
  9. ^ Cloëtta Prize Website Retrieved October 22, 2013
  10. ^ Marcel Benoist Prize 2012 marcel-benoist.ch Retrieved October 22, 2013
  11. ^ SAMS-Member Archived March 4, 2016, at the Wayback Machine samw.ch Retrieved October 22, 2013
  12. ^ Sir Hans Krebs Lecture Archived January 16, 2014, at the Wayback Machine FEBS-EMBO 2014 Retrieved October 22, 2013
  13. ^ First Breakthrough Prize in Life Sciences awarded to Swiss scientist. Archived December 14, 2013, at the Wayback Machine In: University of Basel, December 13, 2013
  14. ^ "Laureates: 2014". Breakthrough Prize in Life Sciences, Retrieved February 5, 2014. Archived from the original on January 6, 2014. Retrieved February 5, 2014.
  15. ^ "ERC Synergy Grant: EUR 11 million for Cancer Research" Archived December 19, 2013, at the Wayback Machine In: University of Basel, December 18, 2013
  16. ^ National Academy of Sciences Members and Foreign Associates Elected. Archived August 18, 2015, at the Wayback Machine nasonline.org Retrieved June 24, 2014
  17. ^ Michael N. Hall: Recipient of the Canada Gairdner International Award, 2015; Gairdner Foundation (gairdner.org); Retrieved March 31, 2015
  18. ^ Debrecen Award for Molecular Medicine 2016 Archived December 22, 2016, at the Wayback Machine; University of Debrecen (unideb.hu); Retrieved May 23, 2017
  19. ^ Doctor honoris causa, University of Geneva 2016; University of Geneva (unige.ch); Retrieved May 23, 2017
  20. ^ Szent-Györgyi Prize 2017 Archived February 15, 2017, at the Wayback Machine; National Foundation for Cancer (nfcr.org); Retrieved May 23, 2017
  21. ^ "2017 Winners".
  22. ^ "Brupbacher Preis". February 13, 2019.
  23. ^ "106th Howard Taylor Ricketts Lecture- "mTOR signaling in growth and metabolism" – University of Chicago – Department of Medicine". University of Chicago – Department of Medicine – Educating Future Doctor's of the World. Retrieved April 25, 2022.
  24. ^ HFSP Nakasone Award: 2019 – Michael Hall
  25. ^ Ansede, Manuel (January 22, 2020). "Premio para los descubridores de un mecanismo para alargar la vida". El País (in Spanish). ISSN 1134-6582. Retrieved January 22, 2020.
  26. ^ "Michael Hall Named 2020 Sjöberg Prize Recipient". nfcr.org. February 28, 2020. Retrieved January 5, 2022.
  27. ^ "Congratulations to Prof. Michael Hall". isrec.ch. October 28, 2021. Retrieved January 5, 2022.
  28. ^ "Dies Academicus 2021". unige.ch. October 15, 2021. Retrieved January 5, 2022.

External links

Retrieved from "https://en.wikipedia.org/w/index.php?title=Michael_N._Hall&oldid=1114318537"