Molsidomine

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Molsidomine
Molsidomine.svg
Identifiers
CAS number 25717-80-0 YesY
PubChem 5353788
ChemSpider 4090 YesY
KEGG D01320 YesY
ChEMBL CHEMBL1256353 N
ATC code C01DX12
Jmol-3D images Image 1
Properties
Molecular formula C9H14N4O4
Molar mass 242.23 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references

Molsidomine is an orally active, long acting vasodilating drug. Molsidomine is metabolized in the liver to the active metabolite linsidomine. Linsidomine is an unstable compound that releases nitric oxide (NO) upon decay as the actual vasodilating compound.[1]

Release of nitric oxide[edit]

Molsidomine.svgSIN-1.svgSIN-1A chemical structure.svg → NO

Molsidomine → Linsidomine (SIN-1) → SIN-1A → nitric oxide[2]

Chemistry[edit]

Molsidomine as well as linsidomine are sydnone imines, a class of mesoionic heterocyclic aromatic chemical compounds.

See also[edit]

References[edit]

  1. ^
    1. REDIRECT Template:Cite pmid
  2. ^ Mutschler, Ernst; Schäfer-Korting, Monika (2001). Arzneimittelwirkungen (in German) (8 ed.). Stuttgart: Wissenschaftliche Verlagsgesellschaft. p. 558. ISBN 3-8047-1763-2.