Bruno Reversade
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Comment: Fundamental WP:NPOV issues. Appears to be written like a CV with endless promotional language praising his work.
Is there by any chance a WP:COI here as well?. WP:PAID confirmed. See userpage for disclosure. Thanks. Willbb234Talk (please {{ping}} me in replies) 21:13, 20 December 2019 (UTC)Comment: The article was cleaned up by ThatMontrealIP and Frietjes and reworked by the COI editor following comments from ThatMontrealIP and Melcous to trim possible puffery and maintain WP:NPOV -- Bbarmadillo (talk) 20:24, 27 December 2019 (UTC)
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Bruno Reversade | |
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Born | 1978 (age 45–46) |
Citizenship | US |
Alma mater | University of California, Los Angeles[1] |
Awards | Society-in-Science, Branco Weiss Fellow (2007), A*STAR Investigator (2008), EMBO Young Investigators (2012) |
Scientific career | |
Fields | Mendelian Genetics, Developmental biology, Micropeptides |
Institutions | |
Doctoral advisor | Edward M. De Robertis |
Other academic advisors | Davor Solter |
Website | www |
Bruno Reversade (born 1978) is an American developmental biologist and human geneticist. He is a Director of the Institute of Medical Biology at A*STAR (Singapore) and holds several faculty positions at other universities. Reversade is known for identifying mutated genes that cause Mendelian diseases in humans and for his research on the genetics of identical twins.[2][3][4]
Early life and education
Bruno Reversade was born in 1978 into a French-American family. He was raised in Grenoble (France) and Washington, D.C. (US).
Scientific career
Reversade became interested in developmental biology in 1997 when studying at the University of Western Ontario (Canada) under the tutelage of Dr. Greg Kelly.[5][6]
He earned his master’s degree at the Pasteur Institute (Paris, France), where he studied head development in the mouse embryo.[5][7] He then moved to the USA to work at the HHMI laboratory of Prof. Edward M. De Robertis at the University of California, Los Angeles. There he studied the specification of the dorsal-ventral axis during vertebrate development using Xenopus embryos.[8] In 2005, Reversade and De Robertis detailed how multiple extracellular proteins allow embryos that are cut in two to self-regulate consistently.[9][10][11]
In 2006, Reversade earned his PhD from the Pierre and Marie Curie University.[12] In 2008, he received the A*STAR investigatorship (Singapore) award and set up his team in 2008 at the Institute of Medical Biology to carry out human embryology and genetic research.[12][1][13] In 2015, he became a Director at A*STAR.[14] Also in 2015, he received AAA Fellowship from the Vrije Universiteit Amsterdam and was appointed Professor of Human Genetics at the Centre for Reproductive Medicine at the University’s Academic Medical Center.[15] Since 2016, Dr. Reversade is a Distinguished Professor of Human Genetics at Koç University (Turkey).[16]
Research areas
Mendelian Genetics
His laboratory works on the genetic characterization and clinical description of monogenic conditions in humans.[17][18] Reversade has identified mutations responsible for progeroid syndromes in humans,[19][20] NLRP1 inflammasome-related diseases,[21][22] and self-healing cancers.[23][21] Reversade’s team has identified germline mutations in the following genes to be responsible for these Mendelian diseases:
Year | Mendelian disease | Gene | Inheritance | Phenotype MIM number |
---|---|---|---|---|
2009 | Cutis laxa, autosomal recessive, type IIB (wrinkly skin syndrome)[19][24] | PYCR1 | Recessive | 614438 |
2010 | Temtamy preaxial brachydactyly syndrome[25] | CHSY1 | Recessive | 605282 |
2011 | Multiple Self-healing Squamous Epithelioma (Fergurson-Smith disease)[26] | TGFBR1 | Dominant | 132800 |
2012 | Hamamy syndrome[27][28] | IRX5 | Recessive | 611174 |
2012 | Punctate palmoplantar keratoderma, type IA[23] | AAGAB | Recessive | 148600 |
2014 | Lissencephaly with Microcephaly 6[29] | KATNB1 | Recessive | 616212 |
2015 | Al-Raqad syndrome[30] | DCPS | Recessive | 616459 |
2015 | Dominant Cutis laxa type 3[20] | ALDH18A1 | Dominant | 616603 |
2016 | Multiple self-healing palmoplantar carcinoma[21][31] | NLRP1 | Dominant | 615225 |
2016 | X-linked syndromic mental retardation 99[32] | USP9X | Heterozygous | 300968 |
2016 | Primary intraosseous vascular malformation[33] | ELMO2 | Recessive | 606893 |
2017 | Cole disease[34] | ENPP1 | Recessive | 615522 |
2017 | Al Kaissi syndrome[35] | CDK10 | Recessive | 617694 |
2017 | Neurogenic Arthrogryposis multiplex congenita with myelin defect[36] | LGI4 | Recessive | 617468 |
2017 | Alkuraya-Kucinskas syndrome[37] | KIAA1109 | Recessive | 617822 |
2017 | Bosma arhinia microphthalmia syndrome[38] | SMCHD1 | Dominant | 603457 |
2018 | Mental retardation, autosomal recessive 63[39][40] | CAMK2A | Recessive | 618095 |
2018 | Tetraamelia syndrome with pulmonary agenesis[41][42][43] | RSPO2 | Recessive | 618021 |
2019 | PAPPA syndrome[44] | TBX4 | Recessive | 601719 |
2020 | Jamuar Syndrome[45] | UGDH | Recessive | 603370 |
Developmental Biology and Identical Twinning
Reversade’s investigations in developmental biology have relied on various animal model organisms (C. elegans, Drosophila, zebrafish, Xenopus and transgenic mice) and covered such embryonic processes as neural induction,[8] limb development,[25][41][44] and various human diseases causing birth defects.[38]
In 2005, during his Ph.D. thesis in the laboratory of Prof. Edward De Robertis, the scientists published two discoveries,[9][46] pertaining to the self-regulation of an embryonic morphogenetic field mediated by the extracellular Chordin/BMP/Sizzled pathway.[10] This helped provide a molecular framework for how embryos split in two halves can develop into perfect, albeit smaller, identical twinned embryos.[47]
Reversade also researches the genetics of dizygotic and monozygotic twinning in humans.[48][5][4] He has been searching for genes responsible for monozygotic twinning from rare population isolates. In December 2008, he traveled to India to collect DNA from the residents of Mohammad Pur Umri village, known for its large number of identical twins.[49] He made a similar trip to Jordan in 2006.[49]
Micropeptides
Reversade’s research is also focused on the annotation of novel micropeptides.[50] In 2013, he discovered and patented a novel hormone named ELABELA (ELA).[50][51] This secreted circulating peptide works as an endogenous ligand for the Apelin receptor (a G protein-coupled receptor).[52][53] The genetic inactivation of ELA leads to cardiovascular defects,[54][55] predisposes to preeclampsia[56][57][58] and is needed for the self-renewal of human embryonic stem cells.[59]
Awards and recognition
- Society-in-Science Branco Weiss Fellowship (2007), ETH Zurich;[60]
- Inaugural A*STAR Investigatorship award (2008), Agency for Science, Technology and Research;[12][49]
- EMBO Young Investigator award (2012), European Molecular Biology Organization;[61][5]
- AAA Fellow (2015), Vrije Universiteit Amsterdam;[15]
- Senior NRF Investigator (2018), National Research Foundation, Government of Singapore.[62]
References
- ^ a b J.P. (2011-01-12). "Out of one, many". The Economist. Singapore. Archived from the original on 2019-12-06. Retrieved 2019-12-06.
- ^ Segal, Nancy L. (2017). Twin Mythconceptions: False Beliefs, Fables, and Facts about Twins. Academic Press. p. 54. ISBN 978-0-12-803994-6 – via Google Books.
- ^ Appasani, Krishnarao, ed. (2012). Epigenomics: From Chromatin Biology to Therapeutics. Cambridge University Press. p. 16. ISBN 978-1-107-00382-8 – via Google Books.
- ^ a b Rosier, Florence. "Sur la piste d'un gène responsable de la gémellité" [On the trail of a gene responsible for twinning]. Le Monde (in French). Archived from the original on 2014-07-08. Retrieved 2019-12-16.
- ^ a b c d Gewin, Virginia (2013-03-21). "Turning point: Bruno Reversade". Nature. 495 (7441). doi:10.1038/nj7441-401a. Archived from the original on 2013-03-26. Retrieved 2019-12-06.
- ^ Kelly, Gregory M; Reversade, Bruno (1997). "Characterization of a cDNA encoding a novel band 4.1-like protein in zebrafish". Biochemistry and Cell Biology. 75 (5): 623–632. doi:10.1139/o97-078.
- ^ Zakin, Lise; Reversade, Bruno; Virlon, Bérangère; Rusniok, Christophe; Glaser, Philippe; Elalouf, Jean-Marc; Brûlet, Philippe (2000-12-19). "Gene expression profiles in normal and Otx2−/− early gastrulating mouse embryos". Proceedings of the National Academy of Sciences of the United States of America. 97 (26): 14388–14393. doi:10.1073/pnas.011513398. PMID 11114168.
- ^ a b Reversade, B.; Kuroda, H.; Lee, H.; Mays, A.; De Robertis, E.M. (2005-06-23). "Depletion of Bmp2, Bmp4, Bmp7 and Spemann organizer signals induces massive brain formation in Xenopus embryos". Development. 132 (15): 3381–92. doi:10.1242/dev.01901. PMID 15975940.
- ^ a b Reversade, Bruno; De Robertis, E.M. (2005-12-16). "Regulation of ADMP and BMP2/4/7 at Opposite Embryonic Poles Generates a Self-Regulating Morphogenetic Field". Cell. 123 (6): 1147–1160. doi:10.1016/j.cell.2005.08.047.
- ^ a b Keeley, Jim (2005-12-16). "Researchers Discover Remarkable Developmental Pathway". Howard Hughes Medical Institute. Archived from the original on 2017-09-25. Retrieved 2019-12-07.
- ^ Martín-Durán, José M.; Vellutini, Bruno C., eds. (2019). Old Questions and Young Approaches to Animal Evolution. Springer Nature. p. 98. ISBN 978-3-030-18201-4. ISSN 2509-6745 – via Google Books.
- ^ a b c "Prestigious A*STAR Investigatorship award attracts outstanding young scientists to carry out independent research at A*STAR Research Institutes" (Press release). Agency for Science, Technology and Research. 2008-02-12. Archived from the original on 2019-12-07. Retrieved 2019-12-07.
- ^ Zengkung, Feng (2012-11-20). "Genetic studies wins A*Star scientist place in elite group". The Straits Times. p. 8. Archived from the original on 2019-12-07. Retrieved 2019-12-07 – via AsiaOne.
- ^ "Bruno Reversade". ResearchGate. Archived from the original on 2019-12-10. Retrieved 2019-12-10.
- ^ a b "Vrije Universiteit Amsterdam Annual Report 2015" (PDF). Vrije Universiteit Amsterdam. 2015. p. 56. Archived from the original (PDF) on 2019-12-07. Retrieved 2019-12-07.
- ^ "Akademik Kadro" [Academic staff] (in Turkish). Koç University. Archived from the original on 2019-12-10. Retrieved 2019-12-10.
- ^ Cheong, Kash (2015-09-18). "Tracking mutated genes that wreak havoc". The Straits Times. Archived from the original on 2015-09-19. Retrieved 2019-12-10.
- ^ Chng, Leonard (2015-10-29). "Asia's Scientific Trailblazers: Bruno Reversade". Asian Scientist. Archived from the original on 2015-10-30. Retrieved 2019-12-10.
- ^ a b Reversade, B.; Escande-Beillard, N.; Dimopoulou, A.; et al. (2009-08-02). "Mutations in PYCR1 cause cutis laxa with progeroid features". Nature Genetics. 41: 1016–1021. doi:10.1038/ng.413.
- ^ a b Fischer-Zirnsak, Björn; Escande-Beillard, Nathalie; Ganesh, Jaya; Callewaert, Bert; et al. (2015-09-03). "Recurrent De Novo Mutations Affecting Residue Arg138 of Pyrroline-5-Carboxylate Synthase Cause a Progeroid Form of Autosomal-Dominant Cutis Laxa". American Journal of Human Genetics. 97 (3): 483–492. doi:10.1016/j.ajhg.2015.08.001. PMID 26320891.
- ^ a b c Zhong, Franklin L.; Mamaï, Ons; Sborgi, Lorenzo; Saad, Ali; et al. (2016-09-22). "Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation". Cell. 167 (1): 187-202.E17. doi:10.1016/j.cell.2016.09.001. PMID 27662089.
- ^ Zhonga, Franklin L.; Robinson, Kim; Teo, Daniel Eng Thiam; et al. (2018-10-05). "Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding". Journal of Biological Chemistry. 293 (49): 18864–18878. doi:10.1074/jbc.RA118.004350. PMID 30291141.
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: CS1 maint: unflagged free DOI (link) - ^ a b Pohler, Elizabeth; Mamai, Ons; Hirst, Jennifer; et al. (2012-10-14). "Haploinsufficiency for AAGAB causes clinically heterogeneous forms of punctate palmoplantar keratoderma". Nature Genetics. 44 (11): 1272–1276. doi:10.1038/ng.2444. PMID 23064416.
- ^ "Scoperta la proteina che contrasta l'invecchiamento precoce della pelle" [The protein that counteracts premature aging of the skin is discovered]. la Repubblica (in Italian). 2009-09-05. Archived from the original on 2011-02-09. Retrieved 2019-12-16.
- ^ a b Tian, J.; Jing, L.; Shboul, M.; et al. (2010-12-10). "Loss of CHSY1, a secreted FRINGE enzyme, causes syndromic brachydactyly in humans via increased NOTCH signaling". American Journal of Human Genetics. 87 (6): 768–78. doi:10.1016/j.ajhg.2010.11.005. PMID 21129727.
- ^ Goudie, D.R.; Merriman, B.; Lee, B.; et al. (2011-02-27). "Multiple self-healing squamous epithelioma is caused by a disease-specific spectrum of mutations in TGFBR1". Nature Genetics. 43 (4): 365–9. doi:10.1038/ng.780. PMID 21358634.
- ^ Bonnard, Carine; Strobl, Anna C; Shboul, Mohammad; et al. (2012-05-13). "Mutations in IRX5 impair craniofacial development and germ cell migration via SDF1". Nature Genetics. 13 (44): 709–713. doi:10.1038/ng.2259. PMID 22581230.
- ^ Goldwert, Lindsay (2012-05-15). "Rare Hamamy syndrome offers genetic insight into what causes heart disease, blood disorders". New York Daily News. Archived from the original on 2017-10-12. Retrieved 2019-12-14.
- ^ Hu, Wen F.; Pomp, Oz; Ben-Omran, Tawfeg; et al. (2014-12-17). "Katanin p80 Regulates Human Cortical Development by Limiting Centriole and Cilia Number". Neuron. 84 (6): 1240–1257. doi:10.1016/j.neuron.2014.12.017. PMID 25521379.
- ^ Ng, Calista K.L.; Shboul, Mohammad; Taverniti, Valerio; et al. (2015-06-01). "Loss of the scavenger mRNA decapping enzyme DCPS causes syndromic intellectual disability with neuromuscular defects". Human Molecular Genetics. 24 (11): 3163–3171. doi:10.1093/hmg/ddv067. PMID 25712129.
- ^ Boh, Samantha (2016-11-02). "Singapore team sheds light on what causes skin cancer". The Straits Times. Archived from the original on 2016-11-02. Retrieved 2019-12-15.
- ^ Reijnders, Margot R.F.; Zachariadis, Vasilios; Latour, Brooke; et al. (2016-02-04). "De Novo Loss-of-Function Mutations in USP9X Cause a Female-Specific Recognizable Syndrome with Developmental Delay and Congenital Malformations". American Journal of Human Genetics. 98 (2): 373–381. doi:10.1016/j.ajhg.2015.12.015. PMID 26833328.
- ^ Cetinkaya, Arda; Xiong, Jingwei Rachel; Vargel, İbrahim; et al. (2016-08-04). "Loss-of-Function Mutations in ELMO2 Cause Intraosseous Vascular Malformation by Impeding RAC1 Signaling". American Journal of Human Genetics. 99 (2): 299–317. doi:10.1016/j.ajhg.2016.06.008. PMID 27476657.
- ^ Chourabi, Marwa; Liew, Mei Shan; Lim, Shawn; et al. (2018-01-08). "ENPP1 Mutation Causes Recessive Cole Disease by Altering Melanogenesis". Journal of Investigative Dermatology. 138 (2): 291–300. doi:10.1016/j.jid.2017.08.045. PMID 28964717.
- ^ Windpassinger, Christian; Piard, Juliette; Bonnard, Carine; et al. (2017-09-07). "CDK10 Mutations in Humans and Mice Cause Severe Growth Retardation, Spine Malformations, and Developmental Delays". American Journal of Human Genetics. 101 (3): 391–403. doi:10.1016/j.ajhg.2017.08.003. PMID 28886341.
- ^ Xue, Shifeng; Maluenda, Jérôme; Marguet, Florent; et al. (2017-04-06). "Loss-of-Function Mutations in LGI4, a Secreted Ligand Involved in Schwann Cell Myelination, Are Responsible for Arthrogryposis Multiplex Congenita". American Journal of Human Genetics. 100 (4): 659–665. doi:10.1016/j.ajhg.2017.02.006. PMID 28318499.
- ^ Gueneau, Lucie; Fish, Richard J.; Shamseldin, Hanan E.; et al. (2018-01-04). "KIAA1109 Variants Are Associated with a Severe Disorder of Brain Development and Arthrogryposis". American Journal of Human Genetics. 102 (1): 116–132. doi:10.1016/j.ajhg.2017.12.002. PMID 29290337.
- ^ a b Gordon, Christopher T; Xue, Shifeng; Yigit, Gökhan; et al. (2017-01-09). "De novo mutations in SMCHD1 cause Bosma arhinia microphthalmia syndrome and abrogate nasal development". Nature Genetics. 49 (2): 249–255. doi:10.1038/ng.3765. PMID 28067911.
- ^ Chia, Poh Hui; Zhong, Franklin Lei; Niwa, Shinsuke; et al. (2018-05-22). "A homozygous loss-of-function CAMK2A mutation causes growth delay, frequent seizures and severe intellectual disability". eLife. doi:10.7554/eLife.32451. PMID 29784083.
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: CS1 maint: unflagged free DOI (link) - ^ Maynard, Christopher (2018-05-23). "Researchers identify a new neurodevelopmental disease". ConsumerAffairs. Archived from the original on 2018-05-24. Retrieved 2019-12-15.
- ^ a b Szenker-Ravi, Emmanuelle; Altunoglu, Umut; Leushacke, Marc; et al. (2018-05-16). "RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6". Nature. 557 (7706): 564–569. doi:10.1038/s41586-018-0118-y. PMID 29769720.
- ^ Voormolen, Sander (2018-05-17). "Geboren zonder armen en benen – nu weten we hoe dat komt" [Born without arms and legs - now we know why]. NRC Handelsblad (in Dutch). Archived from the original on 2019-12-15. Retrieved 2019-12-15.
- ^ Ersan, Mesude (2018-06-11). "Kopan kol ve bacak yeniden çıkabilir... Türk bilim kadınının büyük başarısı" [The broken arm and leg can come out again ... The great success of the Turkish scientist]. Hürriyet (in Turkish). Archived from the original on 2018-11-12. Retrieved 2019-12-15.
- ^ a b Kariminejad, Ariana; Szenker-Ravi, Emmanuelle; Lekszas, Caroline; et al. (2019-12-05). "Homozygous Null TBX4 Mutations Lead to Posterior Amelia with Pelvic and Pulmonary Hypoplasia". American Journal of Human Genetics. 105 (6): 1294–1301. doi:10.1016/j.ajhg.2019.10.013. PMID 31761294.
- ^ Hengel, Holger; Bosso-Lefèvre, Célia; Grady, George; Szenker-Ravi, Emmanuelle; Li, Hankun; Pierce, Sarah; et al. (January 30, 2020). "Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy". Nature Communications. 11 (1). doi:10.1038/s41467-020-14360-7.
- ^ Lee, Hojoon X.; Ambrosio, Andrea L.; Reversade, Bruno; De Robertis, E.M. (2006-01-13). "Embryonic Dorsal-Ventral Signaling: Secreted Frizzled-Related Proteins as Inhibitors of Tolloid Proteinases". Cell. 124 (1): 147–159. doi:10.1016/j.cell.2005.12.018. PMID 16413488.
- ^ Kimelman, David; Pyati, Ujwal J. (2005-12-16). "Bmp Signaling: Turning a Half into a Whole". Cell. 123 (6): 982–984.
- ^ Mbarek, Hamdi; Steinberg, Stacy; Nyholt, Dale R.; et al. (2016-05-05). "Identification of Common Genetic Variants Influencing Spontaneous Dizygotic Twinning and Female Fertility". American Journal of Human Genetics. 98 (5): 898–908. doi:10.1016/j.ajhg.2016.03.008. PMID 27132594.
- ^ a b c Cyranoski, David (2009-04-15). "Developmental biology: Two by two". Nature. 458 (7240): 826–829. doi:10.1038/458826a. PMID 19370006. Archived from the original on 2009-04-17. Retrieved 2019-12-07.
- ^ a b Chng, Serene C.; Ho, Lena; Tian, Jing; Reversade, Bruno (2013-12-23). "ELABELA: a hormone essential for heart development signals via the apelin receptor". Developmental Cell. 27 (6): 672–680. doi:10.1016/j.devcel.2013.11.002. PMID 24316148.
- ^ US patent 20160311880A1
- ^ Murza, Alexandre; Sainsily, Xavier; Coquerel, David; et al. (2016-03-17). "Discovery and Structure–Activity Relationship of a Bioactive Fragment of ELABELA that Modulates Vascular and Cardiac Functions". Journal of Medicinal Chemistry. 59 (7): 2962–2972. doi:10.1021/acs.jmedchem.5b01549.
- ^ Read, Cai; Nyimanu, Duuamene; Williams, Thomas L.; et al. (October 2019). "International Union of Basic and Clinical Pharmacology. CVII. Structure and Pharmacology of the Apelin Receptor with a Recommendation that Elabela/Toddler Is a Second Endogenous Peptide Ligand". Pharmacological Reviews. 71 (4): 467–502. doi:10.1124/pr.119.017533. PMID 31492821.
- ^ Helker, Christian SM; Schuermann, Annika; Pollmann, Cathrin; Chng, Serene C; Kiefer, Friedemann; Reversade, Bruno; Herzog, Wiebke (2015-05-27). "The hormonal peptide Elabela guides angioblasts to the midline during vasculogenesis". eLife. 27 (4). doi:10.7554/eLife.06726. PMID 26017639.
{{cite journal}}
: CS1 maint: unflagged free DOI (link) - ^ Sharma, Bikram; Ho, Lena; Ford, Gretchen; et al. (2017-09-25). "Alternative Progenitor Cells Compensate to Rebuild the Coronary Vasculature in Elabela- and Apj-Deficient Hearts". Developmental Cell. 42 (6): 655-666.E3. doi:10.1016/j.devcel.2017.08.008. PMID 28890073.
- ^ Ho, Lena; van Dijk, Marie; Chye, Sam Tan Jian; Messerschmidt, Daniel M.; et al. (2017-08-18). "ELABELA deficiency promotes preeclampsia and cardiovascular malformations in mice". Science. 357 (6352): 707–713. doi:10.1126/science.aam6607. PMID 28663440.
{{cite journal}}
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(help) - ^ Hassan, Sonia S; Gomez-Lopez, Nardhy (2019-07-06). "Reducing maternal mortality: can elabela help in this fight?". The Lancet. 394 (10192): 8–9. doi:10.1016/S0140-6736(19)30543-4. PMID 31282362.
- ^ Williams, Ruth (2017-06-29). "Anti-Preeclampsia Hormone Discovered". The Scientist. Archived from the original on 2019-12-14. Retrieved 2019-12-14.
- ^ Ho, Lena; Tan, Shawn Y.X.; Wee, Sheena; et al. (2015-10-01). "ELABELA Is an Endogenous Growth Factor that Sustains hESC Self-Renewal via the PI3K/AKT Pathway". Cell Stem Cell. 17 (4): 435–447. doi:10.1016/j.stem.2015.08.010. PMID 26387754.
- ^ "5 Jahre Stipendium «Society in Science»" [5 years of fellowship "Society in Science":Rich Harvest] (in German). ETH Zurich. 2009-02-23. Archived from the original on 2019-12-06. Retrieved 2019-12-06.
- ^ "22 young group leaders recognized as EMBO Young Investigators" (Press release). Heidelberg: European Molecular Biology Organization. 2012-11-14. Archived from the original on 2018-10-29. Retrieved 2019-12-06.
- ^ "Awarded NRF Investigators" (PDF). Government of Singapore. 2018. Archived from the original (PDF) on 2019-12-07. Retrieved 2019-12-07.
External links
Category:Developmental biologists Category:1978 births Category:Vrije Universiteit Amsterdam faculty Category:Koç University faculty Category:Twin studies Category:Embryologists Category:American geneticists Category:Pierre and Marie Curie University alumni
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