(+)-trans-carveol dehydrogenase

Identifiers
EC no.	1.1.1.275
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a (+)-trans-carveol dehydrogenase (EC 1.1.1.275) is an enzyme that catalyzes the chemical reaction

(+)-trans-carveol + NAD⁺ $\rightleftharpoons$ (+)-(S)-carvone + NADH + H⁺

Thus, the two substrates of this enzyme are (+)-trans-carveol and NAD⁺, whereas its 3 products are (+)-(S)-carvone, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is (+)-trans-carveol:NAD⁺ oxidoreductase. This enzyme is also called carveol dehydrogenase. This enzyme participates in monoterpenoid biosynthesis and the degradation of the terpenes limonene and pinene.

References

• Bouwmeester HJ, Gershenzon J, Konings MC, Croteau R (1998). "Biosynthesis of the Monoterpenes Limonene and Carvone in the Fruit of Caraway : I. Demonstration of Enzyme Activities and Their Changes with Development". Plant Physiol. 117 (3): 901–12. doi:10.1104/pp.117.3.901. PMC 34944. PMID 9662532.