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Ribonuclease IV

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Ribonuclease IV
Identifiers
EC no.3.1.26.6
CAS no.61536-76-3
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Ribonuclease IV (EC 3.1.26.6, endoribonuclease IV, poly(A)-specific ribonuclease) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Endonucleolytic cleavage of poly(A) to fragments terminated by 3'-hydroxy and 5'-phosphate groups

This enzyme forms oligonucleotides with an average chain length of 10.

References

  1. ^ Müller WE (November 1976). "Endoribonuclease IV. A poly(A)-specific ribonuclease from chick oviduct. 1. Purification of the enzyme". European Journal of Biochemistry. 70 (1): 241–8. doi:10.1111/j.1432-1033.1976.tb10975.x. PMID 1009928.
  2. ^ Müller WE, Seibert G, Steffen R, Zahn RK (November 1976). "Endoribonuclease IV. 2. Further investigation on the specificity". European Journal of Biochemistry. 70 (1): 249–58. doi:10.1111/j.1432-1033.1976.tb10976.x. PMID 1009929.