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Zerumbone synthase

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Zerumbone synthase
Identifiers
EC no.1.1.1.326
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
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NCBIproteins

Zerumbone synthase (EC 1.1.1.326, ZSD1) is an enzyme with systematic name 10-hydroxy-alpha-humulene:NAD+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction

10-hydroxy-alpha-humulene + NAD+ zerumbone + NADH + H+

The enzyme was cloned from shampoo ginger, Zingiber zerumbet.

References

  1. ^ Okamoto S, Yu F, Harada H, Okajima T, Hattan J, Misawa N, Utsumi R (August 2011). "A short-chain dehydrogenase involved in terpene metabolism from Zingiber zerumbet". The FEBS Journal. 278 (16): 2892–900. doi:10.1111/j.1742-4658.2011.08211.x. PMID 21668645.