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Vijayalakshmi Ravindranath

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Vijayalakshmi Ravindranath
Born (1953-10-18) 18 October 1953 (age 71)
Chennai, India
NationalityIndian
Alma materAndhra University, Mysore University
Known forPromoting neuroscience research and establishing major neuroscience research centres in India
AwardsShanti Swarup Bhatnagar Prize, Padma Shri Award
Scientific career
FieldsNeuroscience
InstitutionsIndian Institute of Science, National Brain Research Centre, National Institute of Mental Health and Neurosciences
Doctoral advisorChandrasekhara N

Vijayalakshmi Ravindranath (born 18 October 1953) is an Indian neuroscientist. She is currently Professor, Centre for Neuroscience, Indian Institute of Science, Bangalore. She was the Founder Director of the National Brain Research Centre, Gurgaon (2000-9) and founder Chair of the Centre for Neuroscience at Indian Institute of Science. Her main area of interest is the study of brain related disorders including neurodegenerative diseases such as Alzheimer's and Parkinson's.[1][2]

Education and career

Ravindranath earned her B.Sc. and M.Sc. degrees from Andhra University and received her Ph.D. (Biochemistry) in 1981 from Mysore University and worked at the National Cancer Institute, USA as a Postdoctoral Fellow. She joined the National Institute of Mental Health and Neurosciences, Bangalore, where she studied the metabolizing capacity of the human brain, focusing especially on psychoactive drugs and environmental toxins.[3] In 1999, she helped Department of Biotechnology (DBT), Government of India to establish National Brain Research Centre (NBRC), an autonomous institution of DBT to co-ordinate and network neuroscience research groups in India. [4]

Awards and recognitions

Ravindranath is an elected fellow of several Indian academies: Indian Academy of Sciences, National Academy of Sciences, Indian National Science Academy and National Academy of Medical Sciences,[5] Indian Academy of Neurosciences and Third World Academy of Sciences.[6]

Publications

  1. Ray, Ajit; Kambali, Maltesh; Ravindranath, Vijayalakshmi (2016). "Thiol Oxidation by Diamide Leads to Dopaminergic Degeneration and Parkinsonism Phenotype in Mice: A Model for Parkinson's Disease". Antioxidants & Redox Signaling. 25 (5): 252–267. doi:10.1089/ars.2015.6602. PMID 27121974.
  2. Johnson, William M.; Golczak, Marcin; Choe, Kyonghwan; Curran, Pierce L.; Gorelenkova Miller, Olga; Yao, Chen; Wang, Wenzhang; Lin, Jiusheng; Milkovic, Nicole M.; Ray, Ajit; Ravindranath, Vijayalakshmi; Zhu, Xiongwei; Wilson, Mark A.; Wilson-Delfosse, Amy L.; Chen, Shu G.; Mieyal, John Joseph (2016). "Regulation of DJ-1 by glutaredoxin 1 in vivo – implications for Parkinson's disease". Biochemistry. 55 (32): 4519–32. doi:10.1021/acs.biochem.5b01132. PMC 4987251. PMID 26894491.
  3. Ravindranath, Vijayalakshmi; Dang, Hoang-Minh; Goya, Rodolfo G.; Mansour, Hader; Nimgaonkar, Vishwajit L.; Russell, Vivienne Ann; Xin, Yu (2015). "Regional research priorities in brain and nervous system disorders". Nature. 527 (7578): S198–206. doi:10.1038/nature16036. PMID 26580328.
  4. Ray, Ajit; Sehgal, Neha; Karunakaran, Smitha; Rangarajan, Govindan; Ravindranath, Vijayalakshmi (2015). "MPTP activates ASK1–p38 MAPK signaling pathway through TNF-dependent Trx1 oxidation in parkinsonism mouse model". Free Radical Biology and Medicine. 87: 312–25. doi:10.1016/j.freeradbiomed.2015.06.041. PMID 26164633.
  5. Ahmad, Faraz; Nidadavolu, Prakash; Durgadoss, Lalitha; Ravindranath, Vijayalakshmi (2014). "Critical cysteines in Akt1 regulate its activity and proteasomal degradation: Implications for neurodegenerative diseases". Free Radical Biology and Medicine. 74: 118–28. doi:10.1016/j.freeradbiomed.2014.06.004. PMID 24933620.
  6. Ravindranath, Vijayalakshmi (2014). Occurrence, distribution and potential actions of CYP2D6 in the brain. pp. 102–116. doi:10.2217/fmeb2013.14.9. ISBN 978-1-78084-462-6. {{cite book}}: |journal= ignored (help)
  7. Ravindranath, Vijayalakshmi; Strobel, Henry W (2013). "Cytochrome P450-mediated metabolism in brain: Functional roles and their implications". Expert Opinion on Drug Metabolism & Toxicology. 9 (5): 551–8. doi:10.1517/17425255.2013.759208. PMID 23330950.

References

  1. ^ "Prof. Vijayalakshmi Ravindranath". Indian Institute of Science. Retrieved 6 October 2014.
  2. ^ Ravindranath, Vijayalakshmi. Lilavathi Daughters (PDF). Retrieved 11 October 2014.
  3. ^ "Archived copy". Archived from the original on 19 August 2016. Retrieved 18 July 2016.{{cite web}}: CS1 maint: archived copy as title (link)
  4. ^ "Wayback Machine" (PDF). web.archive.org. 16 August 2016. Retrieved 16 February 2019.
  5. ^ "List of Fellows - NAMS" (PDF). National Academy of Medical Sciences. 2016. Retrieved 19 March 2016.
  6. ^ "Archived copy" (PDF). Archived from the original (PDF) on 16 August 2016. Retrieved 18 July 2016.{{cite web}}: CS1 maint: archived copy as title (link)
  7. ^ "Career in CSIR". www.csir.res.in. Archived from the original on 10 February 2012. Retrieved 9 August 2015.
  8. ^ "SHRI OM PRAKASH BHASIN AWARDS- HEALTH AND MEDICAL SCIENCES".
  9. ^ "Indian Fellow, Dr V Ravindranath". Indian National Science Academy. Retrieved 6 October 2014.
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