Methanol dehydrogenase (nicotinoprotein)
| Methanol dehydrogenase (nicotinoprotein) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.99.37 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Methanol dehydrogenase (nicotinoprotein) (EC 1.1.99.37, NDMA-dependent methanol dehydrogenase, nicotinoprotein methanol dehydrogenase, methanol:N,N-dimethyl-4-nitrosoaniline oxidoreductase) is an enzyme with systematic name methanol:acceptor oxidoreductase.[1][2][3][4][5] This enzyme catalyses the following chemical reaction
- methanol + acceptor formaldehyde + reduced acceptor
This enzyme contains Zn2+ and Mg2+. N
References
- ^ Vonck, J.; Arfman, N.; De Vries, G.E.; Van Beeumen, J.; Van Bruggen, E.F.; Dijkhuizen, L. (1991). "Electron microscopic analysis and biochemical characterization of a novel methanol dehydrogenase from the thermotolerant Bacillus sp. C1". J. Biol. Chem. 266 (6): 3949–3954. PMID 1995642.
- ^ Van Ophem, P.W.; Van Beeumen, J.; Duine, J.A. (1993). "Nicotinoprotein [NAD(P)-containing] alcohol/aldehyde oxidoreductases. Purification and characterization of a novel type from Amycolatopsis methanolica". Eur. J. Biochem. 212 (3): 819–826. doi:10.1111/j.1432-1033.1993.tb17723.x. PMID 8385013.
- ^ Bystrykh, L.V.; Vonck, J.; van Bruggen, E.F.; van Beeumen, J.; Samyn, B.; Govorukhina, N.I.; Arfman, N.; Duine, J.A.; Dijkhuizen, L. (1993). "Electron microscopic analysis and structural characterization of novel NADP(H)-containing methanol: N,N′-dimethyl-4-nitrosoaniline oxidoreductases from the gram-positive methylotrophic bacteria Amycolatopsis methanolica and Mycobacterium gastri MB19". J. Bacteriol. 175 (6): 1814–1822. PMC 203978. PMID 8449887.
- ^ Hektor, H.J.; Kloosterman, H.; Dijkhuizen, L. (2002). "Identification of a magnesium-dependent NAD(P)(H)-binding domain in the nicotinoprotein methanol dehydrogenase from Bacillus methanolicus". J. Biol. Chem. 277 (49): 46966–46973. doi:10.1074/jbc.M207547200. PMID 12351635.
{{cite journal}}: CS1 maint: unflagged free DOI (link) - ^ Park, H.; Lee, H.; Ro, Y.T.; Kim, Y.M. (2010). "Identification and functional characterization of a gene for the methanol : N,N′-dimethyl-4-nitrosoaniline oxidoreductase from Mycobacterium sp. strain JC1 (DSM 3803)". Microbiology. 156 (Pt 2): 463–471. doi:10.1099/mic.0.034124-0. PMID 19875438.
External links
- Methanol+dehydrogenase+(nicotinoprotein) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)