Uronolactonase

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uronolactonase
Identifiers
EC number3.1.1.19
CAS number9025-93-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, an uronolactonase (EC 3.1.1.19) is an enzyme that catalyzes the chemical reaction

D-glucurono-6,2-lactone + H2O D-glucuronate

Thus, the two substrates of this enzyme are D-glucurono-6,2-lactone and H2O, whereas its product is D-glucuronate.

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is D-glucurono-6,2-lactone lactonohydrolase. This enzyme is also called glucuronolactonase. This enzyme participates in ascorbate and aldarate metabolism.

References[edit]

  • Winkelman J, Lehninger AL (October 1958). "Aldono- and uronolactonases of animal tissues". The Journal of Biological Chemistry. 233 (4): 794–9. PMID 13587494.