Brodimoprim

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Brodimoprim
Brodimoprim.svg
Systematic (IUPAC) name
5-[(4-Bromo-3,5-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine
Clinical data
Legal status ?
Identifiers
CAS number 56518-41-3 YesY
ATC code J01EA02
PubChem CID 68760
ChemSpider 62004 YesY
UNII V1YC7T6LLI YesY
KEGG D07238 YesY
ChEMBL CHEMBL31891 YesY
Chemical data
Formula C13H15BrN4O2 
Mol. mass 339.188 g/mol
 YesY (what is this?)  (verify)

Brodimoprim is a structural derivative of trimethoprim. In brodimoprim, the 4-methoxy group of trimethoprim is replaced with a bromine atom.

As trimethoprim, brodimoprim is a selective inhibitor of bacterial dihydrofolate reductase.[1]

References[edit]

  1. ^ Thomson CJ (1993). "Trimethoprim and brodimoprim resistance of gram-positive and gram-negative bacteria". J Chemother 5 (6): 458–64. PMID 8195838.