Glutathione synthetase

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glutathione synthetase
Identifiers
Symbol GSS
Entrez 2937
HUGO 4624
OMIM 601002
RefSeq NM_000178
UniProt P48637
Other data
EC number 6.3.2.3
Locus Chr. 20 q11.2

Glutathione synthetase (EC 6.3.2.3) is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine, to form glutathione.[1]

[edit] See also

[edit] References

  1. ^ Njålsson R, Norgren S (2005). "Physiological and pathological aspects of GSH metabolism.". Acta Paediatr 94 (2): 132–7. doi:10.1080/08035250410025285. PMID 15981742. 

[edit] External links

 This ligase article is a stub. You can help Wikipedia by expanding it.
v • d • e
Enzymes: ligases (EC 6)
6.1: Carbon-Oxygen
6.2: Carbon-Sulfur
6.3: Carbon-Nitrogen
6.4: Carbon-Carbon
6.5: Phosphoric Ester
6.6: Nitrogen-Metal
v • d • e
Metabolism: amino acid metabolism · synthesis and catabolism enzymes (essential in CAPS)
K→acetyl-CoA
(see below)
G
Other
→succinyl-CoA→TCA
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