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    Black box warnings project

    break a

    I was disturbed to find that some drugs with FDA-mandated Black box warnings have articles that are missing any mention of the box or the risk. It's disturbing to me that someone would create a page and mention minor side effects but leave this out. Looking to drum up interest in a project to programmatically identify and (manually?) remedy all such articles. Anyone? RudolfoMD (talk) 02:31, 4 August 2023 (UTC)[reply]

    Does anyone know of an official list of drugs with black box warnings? WhatamIdoing (talk) 16:53, 4 August 2023 (UTC)[reply]
    Not reliable, but a starting place: https://pharmafactz.com/list-of-black-box-warnings/
    Better ? https://hospitals.vchca.org/images/pharmacy_hca/20200623_BBW.pdf
    SandyGeorgia (Talk) 17:01, 4 August 2023 (UTC)[reply]
    Good question. Neither of those sources lists Brincidofovir.
    I have made a complete list: https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802 (query: https://nctr-crs.fda.gov/fdalabel/ui/#/search/spl-summaries/criteria/343802) using The FDALabel Database. It allows Presence of... specific sections of the prescribing information (e.g., BOXED WARNING) per the main page documentation. It produces a result of >16k labels with boxed warnings. https://nctr-crs.fda.gov/fdalabel/services/spl/summaries/csv/criteria/343802.
    Broad strokes: It seems like it would be appropriate to put the relevant info into wikidata and have https://en.wikipedia.org/wiki/Template:Infobox_drug#Input_from_Wikidata cause it to be displayed.
    RudolfoMD (talk) 05:14, 5 August 2023 (UTC)[reply]
    That could be a useful approach. User:Andrawaag, is this Wikidata idea something that User:ProteinBoxBot could handle? One would ideally want both to have the information added to Wikidata and also to have the bot watch for human-involved errors. WhatamIdoing (talk) 00:18, 6 August 2023 (UTC)[reply]
    Thanks for the feedback and relaying the idea to @Andrawaag. If we proceed, this way, how is sourcing handled? In each article or in Wikidata?
    (Since opening this discussion, someone reverted my fixing the omission of the fact that a drug had a black box warning. That omission is what prompted me opening it. https://en.wikipedia.org/w/index.php?title=Brincidofovir&diff=prev&oldid=1168856210 ) RudolfoMD (talk) 04:51, 12 August 2023 (UTC)[reply]
    @RudolfoMD, I think that a "both/and" approach to sourcing is better than "either/or". Sources are pretty easy to add in Wikidata. It doesn't look easier, at first glance, but all you do is:
    1. Look for "Add references" to the side of whichever detail you're adding a source for, and click on it;
    2. In the confusing little box, start typing in the kind of source you're adding (e.g.,: "URL", "PubMed", "PubChem", or "ISBN");
    3. Choose the correct item from the list (e.g., "PubChem CID" if you have the official compound id number);
    4. Paste the id number/URL into the next field.
    5. Click "publish" for the item (about 2–3 cm above where you originally clicked on "Add references").
    It handles everything else about the citations automatically.
    Here, of course, you need to supply a source. I suspect the reason @Sundayclose reverted you is because you added a source in ==External links== instead of in <ref>...</ref>tags. (For the actual purpose of Wikipedia:External links, your link to PubChem should replace the dead URL that's there now, rather than being added after it, and we don't usually put those in citation templates. I'll go fix that now.) WhatamIdoing (talk) 23:20, 12 August 2023 (UTC)[reply]
    NB: I'm proposing a project to programmatically identify and remedy all such articles. Not go through 16,000 drugs, and for those with articles, perform manual steps on each of a significant fraction of them! Maybe this (WT:MED) isn't a good place to connect with folks with the relevant skills.
    Idea! I'm thinking a smaller / more feasible project would be to add those of the 16,000 drugs with articles to a category - i.e. Drugs with Black Box warnings, and with the https://nctr-crs.fda.gov/ citations on the category page. User:Andrawaag - any thoughts on this (or the original) idea?
    PS This is a good place to establish if it's an uncontroversial bot task; if it is, we could make a WP:BOTREQ - hopefully a good place to connect with folks with the relevant skills. RudolfoMD (talk) 09:46, 1 September 2023 (UTC)[reply]
    RudolfoMD, your ping above to Andrawaag will not be received by them because you added it on to an already existing post. See Help:Notifications; for a ping to work, it has to be a new post with a fresh signature. SandyGeorgia (Talk) 11:03, 1 September 2023 (UTC)[reply]
    About the category idea: How would you handle former black boxes? Remove the category, or keep it (because it used to have one)? WhatamIdoing (talk) 16:02, 1 September 2023 (UTC)[reply]
    It might also be possible to add that information (and a source) as a comment on the US legal status to {{drugbox}}. See Template:Infobox drug/legal status for more information on that. WhatamIdoing (talk) 16:05, 1 September 2023 (UTC)[reply]
    Are most readers in tune to categories? I think the infobox idea might be better ... SandyGeorgia (Talk) 16:48, 1 September 2023 (UTC)[reply]
    Page views say that more readers go to cat pages than editors. (I assumed that they were really just being used by editors, and I asked someone at work to pull the numbers for me. I was wrong. The skew isn't as huge as, say, page views for a popular page like Taylor Swift, but some readers do use them.)
    It would be possible to do both/and. In fact, the infobox could trigger the category. WhatamIdoing (talk) 01:34, 2 September 2023 (UTC)[reply]
    This use of "infobox could trigger the category" sounds like a good concept, but it's against WP:TEMPLATECAT. I've been shot down for taking that approach in other topic-areas, and there definitely does not appear to be consensus to overturn or weaken that recommendation. DMacks (talk) 00:26, 27 September 2023 (UTC)[reply]
    I just noticed: that doesn't seem to have stopped its use twice in the infobox template, e.g. {{main other|[[Category:ECHA InfoCard ID from Wikidata|*]]}}. It seems consensus has changed. Wait... They're hidden maintenance categories... RudolfoMD (talk) 07:05, 10 October 2023 (UTC)[reply]
    Yup, that's a key distinction in the guideline. DMacks (talk) 11:52, 10 October 2023 (UTC)[reply]
    Would something like that {{main other|[[Category:FDA black box warning from Wikidata|*]]}} be appropriate (likewise a hidden maintenance category)? RudolfoMD (talk) 03:35, 5 December 2023 (UTC)[reply]

    break b

    Do other competent authorities have similar schemes - if so should they be considered for addition to articles as well?Nigel Ish (talk) 17:33, 1 September 2023 (UTC)[reply]
    EMA has the inverted triangle, drugs under additional monitoring but not really comparable. Was trying to see if these could be found through DrugCentral, but it doesn't look like it's possible, only get the U.S. labels it seems. fiveby(zero) 17:50, 1 September 2023 (UTC)[reply]
    PMDA has Yellow Letter / Blue Letter, eg. Diclofenac etalhyaluronate "Shock and anaphylaxis by Joyclu 30mg intra-articular injection" fiveby(zero) 18:10, 1 September 2023 (UTC)[reply]
    EMA = UK European Medicines Agency; PMDA = Japan Pharmaceuticals and Medical Devices Agency.
    It's beginning to sound like this is too much for an infobox, and maybe it could be a template similar to {{Medical condition classification and resources}} SandyGeorgia (Talk) 18:38, 1 September 2023 (UTC)[reply]
    Don't let me complicate something that started out as a more straightforward task, just looking for other resources. fiveby(zero) 19:13, 1 September 2023 (UTC)[reply]
    We're already listing regulatory approval in several countries; we could change the infobox item from something like:
    to:
    (Ideally with links under the symbols and citations to support the claim.) WhatamIdoing (talk) 01:38, 2 September 2023 (UTC)[reply]
    I anticipate that
    • US: ℞-only ◼︎
    • EU: Rx-only ▼ would be incomprehensible to a large fraction of users, and
      • US: ℞-only ◼︎⚠️
      • EU: Rx-only ▼⚠️ would be a bit better, but not good... And I agree with fiveby. Success seems more likely if we aim to achieve a small task at scale. At least until someone with bot skills shows interest. (If that's someone already reading or commenting, please speak up; I've not seen anyone say they have any.)
    RudolfoMD (talk) 23:26, 8 September 2023 (UTC)[reply]
    I've got some domain knowledge and could help out with code. I'm a little surprised that there is not an existing bot verifying {{drugbox}}. Looks like CheMoBot by Beetstra and BogBot by Boghog are doing some work, but do not verify against any external compendia. If we go to the trouble of adding a field to the infobox, should probably later add a task to verify the existing fields in passing.
    There's also a little ethical issue here. Once we start supplying drug warnings i think it kind of imposes a duty to be accurate and up-to-date.
    Should get some feedback from those bot authors already touching the infobox before starting. fiveby(zero) 01:06, 9 September 2023 (UTC)[reply]
    Well, after looking at some of the drug articles and thinking about this more, i don't think i want to touch any of those articles, sorry. fiveby(zero) 03:37, 9 September 2023 (UTC)[reply]
    Thanks for that. It would be helpful if you could explain what discoveries led to your hesitance - what hurdle or hurdles your looking at some articles made apparent, especially any surprising ones. (I accept you are free to choose, of course.)
    Would it be right to say that the ethical issue you raise is very close to one that exists for those other bots editing drug articles - in that once a botmaster starts supplying drug info arguably it might impose a duty to keep it up-to-date? Or are they thus far all adding info that can't become out-of-date? I doubt that the FDA often removes black box warnings. RudolfoMD (talk) 08:29, 9 September 2023 (UTC)[reply]
    As far as hurdles go i think the presentation to the reader would require the most consideration and a few other issues would probably arise. Labels are for a drug product which the consumer has in hand whereas the WP articles are for the drug and in some cases drug combinations. Just technical issues which can be overcome and i think what you suggest would be a doable and fairly simple improvement.
    But looking at the drug articles they are listing contraindications, adverse effects, and interactions. They are purporting to provide comprehensive consumer safety information. I'm sure editors are covered by the medical disclaimer, but that is buried in the footer and two clicks away—in my opinion not good enough for the reader. You were disturbed to see the black box warnings missing from articles, i'm leery of attempting to provide drug safety information at all. I would want to have a professional i could trust looking over my shoulder to ensure i was doing things correctly and that it was an actual benefit to the reader vs. simply sending them elsewhere to obtain that information.
    I don't see that the other bots are touching anything that would be a safety issue, tho i could be wrong. fiveby(zero) 15:19, 9 September 2023 (UTC)[reply]
    Glad to see you back at work, RudolfoMD; if you all come to some consensus on this, and can develop a clear algorithm, you're more likely to get attention via a post to Wikipedia:Bot requests. But that shouldn't be initiated without a clear algorithm. SandyGeorgia (Talk) 16:06, 9 September 2023 (UTC)[reply]
    "A clear algorithm" in this case probably means a list of drug articles with the source that supports the claim. Once that information is in hand, it might even be possible to use WP:AWB to do it, especially if the goal is just to put an item in the infobox. WhatamIdoing (talk) 22:30, 9 September 2023 (UTC)[reply]
    But, a list of drugs (and their UNII FDA UNII identifier issued by the FDA / Unique Ingredient Identifier) with the source that supports the claim is in my 05:14, 5 August 2023 (UTC) comment, above. So what is lacking?
    Wikidata
    I looked at adding the info to Wikidata. https://www.wikidata.org/w/index.php?search=Q879952&title=Special%3ASearch&profile=advanced&fulltext=1&ns120=1 indicates that no entries use the property Boxed warning (Q879952) yet, right? So what's a good / is there one correct way to add to WikiData info on which drugs have boxed warnings (i.e. FDA-mandated Black Box Warnings)? I just can't grok what statements I should add.  I don't see that binary values are supported (0/1 or No/Yes...). Can someone add the info for one drug, like maybe add Q879952 in a way they think is correct, for, say, acetaminophen? RudolfoMD (talk) 02:48, 20 September 2023 (UTC)[reply]
    @WhatamIdoing? Anyone? I guess I can resort to BOLD. https://www.wikidata.org/w/index.php?title=Q57055&diff=prev&oldid=1981617113. RudolfoMD (talk) 21:29, 25 September 2023 (UTC)[reply]
    That edit has been reverted.
    Of note Q879952 isn't a property. WikiData's property IDs begin with a P rather than a Q. What you're probably going to have to do is request a new property. I've only ever requested one, and it was a long while ago, but try to put the request in a topic area that's as specific as possible. It's been that long, and processes change, that the only further advise I can give is to look at other property proposals and the help:properties pages. Strike as to not confuse/contradict, see Wostr's response below Little pob (talk) 08:36, 29 September 2023 (UTC)[reply]
    We're already providing terrible warnings - as noted in the OP! " It's disturbing to me that someone would create a page and mention minor side effects but leave this out. " What I've done so far is a massive improvement (or would be if an admin had the ***** to push it live). Do you dispute that? Seems stunningly, blazingly better. RudolfoMD (talk) 03:42, 5 December 2023 (UTC)[reply]

    break c

    I've reverted this edit and discussion between me and RudolfoMD is here. As I suggested there, the first step in this situation should be to initiate a discussion in d:Wikidata:WikiProject Medicine. I also suggested a possible solution: adding boxed warning (Q879952) as a value of a qualifier to legal status (medicine) (P3493) statements like this:

    legal status (medicine) (P3493)
    Normal rank FDA-approved (Q111972129) edit
    has characteristic (P1552) boxed warning (Q879952)
    ▼ 0 reference
    + add reference
    + add value

    However, due to Wikidata being much more detailed than Wikipedia (information that fits into one Wikipedia article is often split into multiple Wikidata items), it is not clear to me right now, whether this type of information should be included in the item describing the active substance or in items describing specific pharmaceutical products like Tylenol (Q3245302). So, as I said, this should be discussed in Wikiproject Medicine in Wikidata first. Sadly, such discussion has not been initiated yet. And as a side note: there is no such thing in Wikidata as be bold policy, given the nature of Wikidata, this type of import of data should be carefully considered and discussed in advance. Wostr (talk) 17:08, 29 September 2023 (UTC)[reply]

    @Wostr, I like your idea of listing these as qualifiers. Am I correct in thinking that approach would also let us add some details, like noting the dates it was active during?
    BTW, after the discussion this week at d:Wikidata_talk:WikiProject_Medicine#diseases_and_rare_diseases, I'm not sure that that page really has the activity necessary to be useful. WhatamIdoing (talk) 16:34, 30 September 2023 (UTC)[reply]
    FYI, all: I got constructive feedback here: https://www.wikidata.org/wiki/Wikidata:Project_chat#Basic_question._How_do_I_mark_that_a_drug_has_a_en:boxed_warning? and edited accordingly before seeing the last 3 comments here. (This new suggestion from Wostr (which they say they had suggested but is not visible to me in their conversation with me - perhaps the edit failed to save or get served properly) seems reasonable. I don't know why Wostr was ignoring my feedback on the idea of asking on Wikiproject Medicine in Wikidata - which included the point WhatamIdoing made - that the page isn't active enough doesn't have the activity necessary to be useful). IMO the Wikidata:Project_chat# is serving adequately. Wostr, do you object to that forum? To presenting your proposal above there if you prefer it to what Andrew Gray proposed and I want to go with? So, as a side note, I see https://www.wikidata.org/wiki/Wikidata:Be_bold does exist as a guideline, and my two edits of paracetamol (Q57055) after seeking input were highly consistent with it. RudolfoMD (talk) 02:34, 1 October 2023 (UTC)[reply]
    Oh, and @Ozzie10aaaa , what was this edit about? Makes it look like I added the medicine sign. https://en.wikipedia.org/w/index.php?title=Wikipedia_talk%3AWikiProject_Medicine&diff=prev&oldid=1152801192 RudolfoMD (talk) 02:57, 1 October 2023 (UTC)[reply]
    I usually add images to interesting posts (like this one ) to hopefully attract more attention (anyway I've removed it)--Ozzie10aaaa (talk) 12:40, 1 October 2023 (UTC)[reply]
    To "hopefully attract more attention"? Interesting... How, exactly? Whose attention does it target? Via some sort of watchlist type scheme? Why did you then remove it? Are you going to stop making such edits? Or do them differently so attribution is clear? RudolfoMD (talk) 19:35, 3 October 2023 (UTC)[reply]
    @Ozzie10aaaa? RudolfoMD (talk) 06:35, 5 October 2023 (UTC)[reply]
    I've been requesting that Ozzie stop making those (unhelpful) edits for years. They not only create the problem RudolfoMD mentions-- they also add unnecessarily to WT:MED participant watchlists, while adding nothing to the discussion. I've never seen a reason why Ozzie does it. SandyGeorgia (Talk) 12:49, 1 October 2023 (UTC)[reply]
    Odd Ozzy silence above. Not a good look. How does this image connect to a project watchlist, I wonder. RudolfoMD (talk) 06:28, 10 October 2023 (UTC)[reply]
    She means that when you make a small edit, it appears in Special:Watchlist, even if the edit didn't add anything that you think is substantive. This can be draw attention to the section, because some people will see the image being added and consequently also see the section it was added to, but it does entail a little bit of extra work for people who are checking every edit (as opposed to people like me, who check all the edits at once). I'd rather see an image added than to see a comment that says "bump" or "adding a comment so it won't be archived", but everyone is going to have their own personal preferences.
    Also, @RudolfoMD, I see that yesterday was your six-month anniversary on Wikipedia. Welcome. WhatamIdoing (talk) 00:05, 11 October 2023 (UTC)[reply]

    break d

    @WhatamIdoing: It depends. FDA-approved (Q111972129) can be seen here as a 'main' statement, so every qualifier applies to this particular statement and you can't have a qualifier added to a qualifier (second level of qualifiers), so you can't add an additional information that would apply for boxed warning (Q879952). Every date you add here, like start time (P580), would apply to FDA-approved (Q111972129) and not to boxed warning (Q879952).
    I'm not really familiar with the US pharmaceutical law and I don't know how boxed warning (Q879952) is issued by the FDA. My example above would mean in WD something like: FDA approved paracetamol as a drug and every drug containing paracetamol in the US must be sold with a black box warning ≈ FDA approval is closely related to the obligation to indicate a black box warning. This is the simplest solution here I can think of, however, adding references to such a statement could be not so simple and would require using applies to part (P518) (main statement/qualifier) in the references section if there was no single source for information about FDA approval and black box warnings.
    You need to think about the scope of information you need for boxed warning (Q879952). Do you want to specify that the black box warning should be placed from a certain date? Or for certain doses etc.?
    @RudolfoMD: I still don't know why some parts of my comments on my talk page are not properly visible for you. And I still suggest that proper discussion should be conducted in WD, because any consensus reached here has no validity in WD. d:Wikidata_talk:WikiProject_Medicine#diseases_and_rare_diseases mentioned here as a example is in fact an interesting discussion which I followed from the beginning, although I did not participate in it. We had similar in chemistry and in many other areas in WD. To put it very briefly: ontologies (not only in WD) are logical but in many cases counter-intuitive. But it also shows that there is some exchange of views in this project, it is not dead, so an attempt to discuss this topic there is not a priori doomed to failure.
    Be bold in WD states that On Wikidata, no clear policy of this kind exists, and the following is thus just an emerging guideline. The page was created by an en.wiki user, edited thrice and never approved as any guideline (I corrected the false template on this page). This doesn't mean you can't make undiscussed edits. However, these types of edits, without specific preparation, often hit a wall in the form of Wikidata's complexity. Wostr (talk) 19:37, 1 October 2023 (UTC)[reply]
    I added sourcing thus: https://www.wikidata.org/w/index.php?title=Q879952&diff=prev&oldid=1981610608
    Do you want to specify that the black box warning should be placed from a certain date? Or for certain doses etc.? No, I haven't proposed that. That's not in the source indicated above, is it? (and which, incidentally, it seems should be put into an online spreadsheet.)
    Good, so Wikidata:Project_chat# is serving adequately- I see no objection.
    On to proceed to seek help with the importing? RudolfoMD (talk) 07:59, 5 October 2023 (UTC)[reply]
    The easiest way to import a large set of data is to use d:WD:QS (or a bot). But the first thing (regardless of the import method) is to prepare the data. If [1] is the dataset, I don't see right now an easy way to associate an entry from this dataset with an item in WD. These entries are for pharmaceutical products, not for active substances. There are UNII numbers, however, if there is an entry for 'Epzicom' does it mean that the 'black box warning' statement should be added to Epzicom (Q47499269), abacavir/lamivudine (Q4663143), lamivudine (Q422631), abacavir (Q304330) or abacavir sulfate (Q27105640)? This should be sorted out first, before thinking about the method of import. d:WD:QS is one way to do it, if you have a prepared dataset. Association based on UNII may work, but it won't be perfect, there may be many incorrect additions (judging on previous mass imports that were based on only one identifier). There is also meta:Mix'n'match/Manual tool. It's not an automatic tool and way slower than QS, but may yield better results here. Wostr (talk) 17:40, 5 October 2023 (UTC)[reply]
    Once again, you come across as throwing up roadblocks. Surely you know I want to use QS but can't yet and that I'm arguing that this is the way to do it, which you've surely seen, and unlike my previous edit, haven't reverted. There is an entry in the table for all four, so abacavir/lamivudine (Q4663143), lamivudine (Q422631), abacavir (Q304330) and abacavir sulfate (Q27105640)? should all have the same. I believe I already stated that it's not selected brands, but APIs that the warnings are mandated for. I don't see how to use the UNII with quicksource, but would welcome help/guidance; as I mentioned, I want to use 'em if they'd improve the import. You say "These entries are for pharmaceutical products, not for active substances" but they are the latter too. We can ignore the per-row redundancy. Is there a previous mass import based on UNII and government data where there were many incorrect additions that you can point to? What's your concern exactly? Are you claiming the FDA's own data on its own actions is highly erroneous? That's quite a claim. I'll look at Mix'n'match.
    At least on .en, the API is used for article names, and the appropriate infoboxes would be tweakable to use the info to display something like
    as suggested above. RudolfoMD (talk) 05:24, 9 October 2023 (UTC)[reply]
    As a lay reader; US: ℞-only ◼︎⚠️ is no more understandable than US: ℞-only ◼︎ and looks awkward when you know the intent is to indicate the same idea. Can we explain what the ◼︎ and ▼ mean instead?
    Here are some ways of doing this (with some comments of potential drawbacks):
    • link them to boxed warning – though might have to ignore that we're duplicating wikilinks when there is more than one regulatory body warning, unless there are articles for the equivalent from non-USA bodies (example, the EMA)
    • link to an {{anchor}} within the article – does require the content to exist
    • adding a {{tooltip}} – would need to consider wording as "has a boxed warning" is just as unhelpful and it is not possible to wikilink within a tooltip (though the tooltip itself can be wrapped in a wikilink)
    • using {{efn}} + {{notelist}} – this is my preferred solution and I'm struggling to argue against it (whilst the MOS for infoboxes discourages references that are used elsewhere in the article, there is no mention of other types of footnote. H:FN seems to have no problem with footnotes within an infobox either)
    These are off the top of my head, there are probably alternatives. Little pob (talk) 13:04, 9 October 2023 (UTC)[reply]
    I'm just trying to handle the FDA warnings, at least to start - seems plenty complicated. In general, the content doesn't exist, which precludes {{anchor}} at least most of the time and at least as an initial solution. I am not familiar with {{efn}} + {{notelist}}. What would that look/code like? I'm guessing/sounds complicated.
    Maybe something like this would be good for what appears in the drugbox, speaking of complicated, under US, in the Legal Standard section. (Warning in a black box):
    or
     !? (clickable!) (I guess with {{efn}} + {{notelist}} something similar but better could be achieved?) RudolfoMD (talk) 05:16, 10 October 2023 (UTC)[reply]
    Using {{efn}} could look something like the examples here: User:Little pob/scratchpad
    As others have alluded to WP:NOMED, have kept the footnotes generic rather than along the lines of "FDA says X when taking this medication". Little pob (talk) 09:14, 10 October 2023 (UTC)[reply]
    I'd love to get this to work. If there's no notes section, this doesn't degrade gracefully, and I've no idea how to get the notes {{notelist}} section added to the hundreds of articles it would need. Perhaps there's a bot that does that already when it sees it's needed. I could test to find out? RudolfoMD (talk) 17:31, 30 November 2023 (UTC)[reply]
    1. If you want to call them roadblocks, go ahead. Without my initial intervention, you could have added thousands of entries to WD, which would then all have to be deleted. Now, slowly, the idea of adding this information is taking shape and may become valuable information in WD. I spent many years in WD, millions of edits in the field of chemical compounds, and I have already seen many different cases where hasty actions led to the need for mass corrections, deletions, merging, etc.
    2. I don't see how to use the UNII with quicksource, but would welcome help/guidance – the way I see it, you would have to download the FDA data, download all the WD items with UNII (two .xls spreadsheets) and then properly compare both files based on UNII so that you are left with a list of items in WD for which there is a corresponding record on the FDA list.
    3. This is not the problem with FDA data, it's the problem of the data in WD. In the past there were many mass imports, most of the importers didn't care about the data consistency. In many cases we also did not have defined procedures and data models. This means that existing data problems in WD (e.g. unresolved constraint violations) cause errors to propagate to subsequent statements/items during such imports. A solution such as mix'n'match, which involves semi-automatic and manual addition of statements, is much more resistant to such problems; the use of QS, in which you are not able to manually review thousands of results and the entire adding process will take little time, is more susceptible – and in the past, QS imports based on only one identifier, e.g. the CAS number, led to many errors.
    4. It is also possible that the information would first be added to the infoboxes in en.wiki, and then exported to WD as there are tools for that. Only then it would be a duplication of work, because data from WD can be imported automatically to the infoboxes in en.wiki.
    5. By the way, seeing the proposal of what it could look like in the infobox and as an advocate for accessibility in my home wiki, I would like to point out your Wikipedia:Manual of Style/Accessibility guidelines. Probably, an image with an alt= attribute or abbr tag for this unicode character would be sufficient. Wostr (talk) 14:58, 9 October 2023 (UTC)[reply]
    1. I sought feedback and got none, so I made one edit, and got some. I continue to proceed prudently.
    I've just edited a second item. I intend to use QS on a handful of items and scale up in steps, checking the results and leaving time for others to do the same.
    2. I don't follow. As I said twice, I want to use 'em if they'd improve the import. Not seeing an argument that they would. At the moment, it seems baroque - an unnecessary complicated detour around an ... obstacle.
    3. Of course there have been bulls in the china shop. But it's important to not forget why Wikipedia works, and Nupedia didn't. I could well be wrong, but mix'n'match does not seem appropriate, as I don't anticipate much of the ambiguity it's designed to help with.
    4. I see Albendazole is pulling data from WikiData. I can see the wikitext in the template, but can't make heads or tails of it:
    (<code> ::::::: from Wikidata :::::::| label99 = [[ECHA InfoCard|<span title="echa.europa.eu">ECHA InfoCard</span>]] :::::::| data99 = {{#if:{{#property:P2566}} | [https://echa.europa.eu/substance-information/-/substanceinfo/{{#property:P2566}} {{#property:P2566}}]{{EditAtWikidata |pid=P2566}}{{main other|[[Category:ECHA InfoCard ID from Wikidata|*]]}}}} :::::::</code>)
    - RudolfoMD (talk) 06:21, 10 October 2023 (UTC)[reply]
    2. Now I don't follow either. Quickstatements is an extremely powerful tool. In minutes or hours, you can do work that would normally take months of manual editing. However, the problem at the beginning is always the preparation of data that is then used in QS. For example, in recent months, using Wikidata Query Service and Quickstatements, I made tens of thousands of edits – in 30 seconds I could prepare the data allowing me to make 20,000 edits in QS (which were performed automatically). It appears that there are at least several thousand edits, if not a dozen, to be made to add the FDA data. From my point of view, it seems reasonable, instead of making these edits manually, to first properly process the data, and then be able to run QS and make all the edits automatically. In my opinion, it would be a big time saver, but I'm not going to impose this on you. I am presenting the possibilities that I know about.
    4. While I am maintaining the equivalent of the Chembox template in pl.wiki, both projects are far from each other in terms of technical solutions. Based on what I see I think that the easiest way to import data from WD to en.wiki infobox would be to use something like: 
    {{#ifeq:{{#invoke:String|match|s={{#property:P3493}}|pattern=boxed warning|plain=true}}|boxed warning|output}}
    ('String' module with 'match' function checks if the imported values of P3493 property contain 'boxed warning' statement; if yes, the result is then checked using 'ifeq' function and displays an 'output' text; you can test this in e.g. paracetamol in edit preview). However, this is a very clumsy solution, it would be best to write it in an appropriate module in Lua. Wostr (talk) 18:55, 10 October 2023 (UTC)[reply]
    PS There is also d:Wikidata:Tools/OpenRefine. Maybe this tool will help. Wostr (talk) 12:01, 12 October 2023 (UTC)[reply]
    2. I spotted the/a source of our confusion. What I've been saying is I want to use UNIIs iff they'd improve the import. I think you were reading a pronoun as referring to something else (QS or mix'n'match). Note, I said, "I intend to use QS on a..."
    4. Thanks! {{#ifeq:{{#invoke:String|match|s={{#property:P3493}}|pattern=boxed warning|plain=true}}|boxed warning|<math>\begin{array}{|} \hline W\!ARNING \\ \hline \end{array}</math>}} works at [2] and is a no-op at [3]. That's helpful. And thanks to my edits with mix'n'match, now I'm eligible to use QS. So thanks for that too. Now where to put it to get it in the infobox.... RudolfoMD (talk) 18:39, 12 October 2023 (UTC)[reply]
    Haven't been feeling up to tackling this Template work. Anyone I can pass the torch to? RudolfoMD (talk) 02:54, 19 October 2023 (UTC)[reply]
    @RudolfoMD, is https://en.wikipedia.org/w/index.php?title=Template:Infobox_drug/sandbox&diff=prev&oldid=1179456993 the most recent (relevant) edit? WhatamIdoing (talk) 01:36, 20 October 2023 (UTC)[reply]
    That was an exploratory attempt to try to grok how the drugbox template works, but was sort of the last edit, yes. Wasn't able to learn from it/see any effect. Emphasis on the edit summary - BREAKING #99 to test / explore stuff. OK to revert.. But the code above at "4." seems like a good next step, using what Woster wrote ; I made that more recently. RudolfoMD (talk) 05:38, 20 October 2023 (UTC)[reply]
    I haven't figured out how to preview the impact of edits to the template sandbox on an article such as Paracetamol where I want to appear. RudolfoMD (talk) 09:53, 21 October 2023 (UTC)[reply]
    * Pppery * , can you help? I see you made a requested edit at Template_talk:Infobox_drug. RudolfoMD (talk) 10:06, 21 October 2023 (UTC)[reply]
    I have no interest in reading through this entire wall of text to see what needs to be done, and it appears Paine is already on it, so no. * Pppery * it has begun... 15:13, 21 October 2023 (UTC)[reply]
    Or P.I. Ellsworth , or User:Arthurfragoso, can you help? Ditto. I see you made a requested edit at Template_talk:Infobox_drug. RudolfoMD (talk) 10:10, 21 October 2023 (UTC)[reply]
    Template:Infobox drug/testcases doesn't have any testcases that source from wikidata? RudolfoMD (talk) 10:12, 21 October 2023 (UTC)[reply]
    |legal_US_comment= {{{legal_US_comment|}}}??? RudolfoMD (talk) 10:24, 21 October 2023 (UTC)[reply]
    To editor RudolfoMD: I do intend to go back over and read this entire block of text, but for now it appears that you want a warning box to appear in articles, such as at Template:Infobox drug/testcases-warning. That's a page I created to test the warning box specifically, although I see it in many of the other test cases I viewed. I'm no Wikidata expert, but it seems that the data from WD is not drawn in preview, so we must rely on test cases to check for the warning box. As I said, I'm no expert, but it does appear to work. Hope this helps. P.I. Ellsworth , ed. put'er there 11:11, 21 October 2023 (UTC)[reply]
    Looks like earlier you mentioned Brincidofovir – checked that one in preview and the warning box appears, so I seem to be wrong about Wikidata, and I don't have a clue why the boxes don't appear in the Paracetamol article. (???) Need to dig more and I do wish that editor DePiep could be available, because they've done so much work on these chem pages. P.I. Ellsworth , ed. put'er there 12:43, 21 October 2023 (UTC)[reply]
    Thanks for the replies.
    Paine, how does one check Brincidofovir in preview of Template:Infobox_drug/sandbox as you did (or I think you're saying you did) to see if the warning box appears? Is there a URL you can share that previews what Brincidofovir (or Paracetamol) looks like with Template:Infobox_drug/sandbox?
    The gist is, I'm wanting help with editing Template:Infobox_drug/sandbox. I've made some edits but I'm skeptical I got 'em right, and I can't figure out how to test 'em.
    Context: I've got a list of ~1600 drugs that have FDA-mandated black box warnings and so far I've marked a few of them manually in wikidata and intend to mark the rest. I think it indicates consensus to use something like {{#ifeq:{{#invoke:String|match|s={{#property:P3493}}|pattern=boxed warning|plain=true}}|boxed warning|[[Boxed warning|<math>\begin{array}{|} \hline W\!ARNING \\ \hline \end{array}</math>]]<ref name="FDA-AllBoxedWarnings">{{cite web |title=FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.) |url=https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802 |website=nctr-crs.fda.gov |publisher=[[FDA]] |access-date=22 Oct 2023}}</ref>}} in Template:Infobox_drug/sandbox to make a warning appear in response to the wikidata. [Note, this is the previously posted code snippet but modified to link to boxed warning, and have a reference, as of course it should, but now it's much longer. ] [PPS: Edit: Whoops, forgot, User:Little_pob/scratchpad is the plan. I should be sleeping, not editing, right now.]
    (PS My bad paging 3 people, expecting maybe 1 would respond. Lesson learned. And not initially providing a clearer summary of the need, so you don't have to read this long, noisy thread.) RudolfoMD (talk) 08:11, 22 October 2023 (UTC)[reply]
    Thank you for that! No problemo. To check in preview, I just go to the article, bring up the edit screen, add the sandbox to the code such as in {{Infobox drug/sandbox, and then click on Show preview. When I do this in the Brincidofovir article, the Warning box does appear. So what I've learned is that if the Wikidata item is correct, then the infobox in the article will be correct, even in preview. I've also learned that we cannot go by the test cases. They might show the Warning box while the infobox in an article might not, as was in the case of Template:Infobox drug/testcases-warning#Paracetamol. We seem to be almost there, but not quite. Another tip is to be sure to use the full template name, "Infobox drug", when you preview the sandbox in an article. You might get an erroneous outcome for those which use the redirect, {{drugbox}}. So, in other words, {{drugbox/sandbox in preview might not work as expected, so instead, be sure to use {{Infobox drug/sandbox. P.I. Ellsworth , ed. put'er there 11:25, 22 October 2023 (UTC)[reply]
    My primary concern regarding the warning box image is the space it occupies in an already constrained area. Initially, I wanted to highlight the linebreak between the box and the reference, as seen in the Brincidofovir testcases-warning. Adjusting this by a few pixels could potentially address the issue. However, upon closer inspection, I noticed another opportunity for space optimization: the repeated "Legal status" label, as illustrated in this image (for the 2C-B drug). I'm uncertain if simply implementing a colspan="2" would be the solution, given potential style disruption, but I wanted to offer this perspective for brainstorming purposes. Arthurfragoso (talk) 11:05, 26 October 2023 (UTC)[reply]
    Your primary concern is no small issue, as I also have thought that the warning box would be helped by a bit smaller rendering of it in the ibox. Perhaps a new template ({{Warning box}}) is needed that has a parameter for size adjustment? or maybe the size can be controlled/decreased in Wikidata? P.I. Ellsworth , ed. put'er there 12:10, 26 October 2023 (UTC)[reply]
    I have the template working now. @Arthurfragoso, your optimization eliminates the link to Regulation_of_therapeutic_goods. I presume avoiding that is the reason behind the repeated "Legal status" label.
    I don't know how to make the warning box resizable or make the template's subheadline a wikilink. Both changes are nice-to haves, but out of scope. Either could be worked on anytime, once someone with the relevant skills shows/expresses interest. In the mean time there's a fix to the disturbing, important issue that some drugs with FDA-mandated Black box warnings have articles that are missing any mention of the box or the risk. A fix that I struggled for some time to accomplish. RudolfoMD (talk) 01:45, 15 November 2023 (UTC)[reply]
    Wostr, that code doesn't seem to work when I put it in Template:Infobox drug/sandbox. Any idea what's wrong? PE, Arthur: feel free to improve it (Template:Infobox drug/sandbox). I can't manage to debug it. Willing to help? RudolfoMD (talk) 08:16, 4 November 2023 (UTC)[reply]
    As I said, this is not a sophisticated solution, but it should work in any article as long as there is a statement in P3493 in WD with a label 'boxed warning'. It won't work on a template page. I'm not a maintainer of en.wiki infoboxes, I wouldn't want to mess with them. Wostr (talk) 08:41, 4 November 2023 (UTC)[reply]
    After a bunch of dead ends I figured out my mistakes and got it working in the sandbox. RudolfoMD (talk) 01:52, 15 November 2023 (UTC)[reply]
    I could use some help (e.g. at Template_talk:Infobox_drug) getting this live. Whether that's an admin deciding it's good enough to make live and improve later or anyone helping to improve it first. RudolfoMD (talk) 10:06, 24 November 2023 (UTC)[reply]
    This appears to be hung up by one editor's worries about uncited information on Wikidata by other parts of the template. WhatamIdoing (talk) 16:47, 28 November 2023 (UTC)[reply]
    Thank you so much for elucidating that to be the case more than I could. I was/am at wit's end, felt personally attacked. I'm not sure if it helps, but I just made Template:Drugboxwarns which differs from https://en.wikipedia.org/wiki/Template:Infobox Drug] only by the change I'm asking be copied to it. I could make a new request based on it; it would me requesting the same change, but arguably more simply; not sure if that would be appropriate application of the KISS principle. RudolfoMD (talk) 02:43, 29 November 2023 (UTC)[reply]
    I ("WARNING...") have it working (in the sandbox) with simple CSS. Needs a nudge. RudolfoMD (talk) 03:30, 5 December 2023 (UTC)[reply]
    Oh, and I'm working on using OpenRefine. I made an initial import of ~90 entries. RudolfoMD (talk) 22:37, 6 November 2023 (UTC)[reply]
    It's largely done - there are ~~900 drugs with property Boxed warning (Q879952), sourced up from 0. RudolfoMD (talk) 02:35, 2 December 2023 (UTC)[reply]
    Yay! Bravo, all. Template is live. There's still work for me/us left - e.g. NIRMATRELVIR AND RITONAVIR (Nirmatrelvir/ritonavir is one of the drugs I/OpenRefine failed to mark in wikidata; not sure why. Need to get the import/match to work better. I wonder how many pages the warning is displayed on.
    Further discussion: https://en.wikipedia.org/wiki/Wikipedia_talk:WikiProject_Medicine#Black_box_warnings_2nd_project RudolfoMD (talk) 01:47, 8 December 2023 (UTC)[reply]

    Good article reassessment for Bipolar disorder

    Bipolar disorder has been nominated for a good article reassessment. If you are interested in the discussion, please participate by adding your comments to the reassessment page. If concerns are not addressed during the review period, the good article status may be removed from the article. ~~ AirshipJungleman29 (talk) 19:20, 6 December 2023 (UTC)[reply]

    thanks for post--Ozzie10aaaa (talk) 13:50, 16 December 2023 (UTC)[reply]

    New student-created article

    A student created a new article on Ovarian squamous cell carcinoma. Give the length of the article, I don't feel confident doing even a basic once-over to make sure it doesn't content anything risky. And since it comes from an advanced pharmacology class rather than a medical class, I don't want to just assume it's probably good.

    I have no specific concerns about the article - it looks mostly ok to me - but I would really appreciate if someone could take a critical look at it. Thanks all! Ian (Wiki Ed) (talk) 17:19, 8 December 2023 (UTC)[reply]

    @Ajpolino, Colin, Keilana, and Johnbod: SandyGeorgia (Talk) 17:48, 8 December 2023 (UTC)[reply]
    I'm not at all competent to check it. I've tried to de-orphan it by linking at Ovarian cancer & Squamous-cell carcinoma, I hope correctly. Johnbod (talk) 18:06, 8 December 2023 (UTC)[reply]
    @Sarcomadoc is a new editor who might be able to spot problems. MastCell would be another good option, but I don't know if he's around. WhatamIdoing (talk) 18:47, 8 December 2023 (UTC)[reply]
    I looked it over and saw nothing obviously concerning. That's quite an impressive article for a new editor. WhatamIdoing (talk) 18:45, 8 December 2023 (UTC)[reply]

    Can someone access the source from which the Advantages and Limitations table comes in this section? The text of the source gives some indication we may need to be concerned about copyright, but I can't see the tables. SandyGeorgia (Talk) 18:55, 8 December 2023 (UTC)[reply]

    Some of the text in the table appears to be copied from text in the source. The source does not contain the same table. --Whywhenwhohow (talk) 20:20, 9 December 2023 (UTC)[reply]

    @SandyGeorgia: I can take a look this weekend. Keilana (talk) 23:06, 9 December 2023 (UTC)[reply]

    Keilana are you able to deal with the copyright issues raised by Whywhenwhohow? I don't have access ... SandyGeorgia (Talk) 23:54, 9 December 2023 (UTC)[reply]
    @SandyGeorgia: Got super busy at work and forgot about this, but I'm taking a look now with institutional access. Keilana (talk) 18:01, 27 December 2023 (UTC)[reply]

    Another

    Alzheimer's disease and COVID-19 is from the same course, and is going to need a look. SandyGeorgia (Talk) 00:13, 9 December 2023 (UTC)[reply]

    FAR for Reactive attachment disorder

    User:Buidhe has nominated Reactive attachment disorder for a featured article review here. Please join the discussion on whether this article meets the featured article criteria. Articles are typically reviewed for two weeks. If substantial concerns are not addressed during the review period, the article will be moved to the Featured Article Removal Candidates list for a further period, where editors may declare "Keep" or "Delist" in regards to the article's featured status. The instructions for the review process are here. MediaWiki message delivery (talk) 19:32, 8 December 2023 (UTC)[reply]

    Categories related to drug brands

    This discussion about renaming categories related to drug brands may be of interest. --Whywhenwhohow (talk) 20:24, 9 December 2023 (UTC)[reply]

    commented--Ozzie10aaaa (talk) 13:00, 11 December 2023 (UTC)[reply]
    The proposal is to rename the "BigPharma brands" categories (e.g., Category:Bayer brands) to "BigPharma drugs". I've asked for information about how they intend to handle the non-drug brands (e.g., Centrum (multivitamin), which is owned by a corporation spun off from GSK plc; Nature Made, which is owned by a company owned by Otsuka Pharmaceutical; One A Day, which is owned by Bayer). WhatamIdoing (talk) 18:21, 11 December 2023 (UTC)[reply]

    Most important medical articles?

    See ongoing discussions at Wikipedia:Vital articles/Level/5/Biological and health sciences/Health and the current list at Wikipedia_talk:Vital_articles/Level/5/Subpage_4#Health,_medicine,_and_disease and feel free to suggest what is missing or needs to be swapped :) Piotr Konieczny aka Prokonsul Piotrus| reply here 09:20, 10 December 2023 (UTC)[reply]

    If someone wants to engage with this, the breakdown is:
    They are looking for a couple hundred suggestions about what to put in that last group.
    @Piotrus, for the last 10 years or so, we have tried to keep Category:Top-importance medicine articles to 100 articles and Category:High-importance medicine articles to 1,000 articles, although I haven't checked them for a while (sometimes an inexperienced or optimistic editor declares their favorite subject to be our top priority, in the misguided hope that we'll focus on their article first). These categories should probably align pretty closely with the vital articles lists. WhatamIdoing (talk) 18:34, 11 December 2023 (UTC)[reply]
    @WhatamIdoing Thanks, that's good to know. I see the assessments count at 100 and 1,071, but I am not aware of how to check which artcles were assed most recently (i.e. what may be the 71 extras). In either case, that's quite useful. Piotr Konieczny aka Prokonsul Piotrus| reply here 23:32, 11 December 2023 (UTC)[reply]
    @TonyTheTiger Perhaps you know if there's a way to check what we list at vital vs the assessmens here? Wikidata query might be possible.
    There is a lot of mismatch with what we list and what is not high+. Ex. from recent proposals, from those I checked, Syringe is mid, Hypodermic needle is low, scalpel is low, Bandage is low (seriously?), Sling (medicine) is mid (a pathethic stub too, folks...), Crutch is mid, Splint (medicine) is mid, Tourniquet is mid. Ventilator is mid. Only stretcher lucked out as being high. I wonder if there is some rating bias against tools (which is what Tony has recently proposed as additions)? @WhatamIdoing Piotr Konieczny aka Prokonsul Piotrus| reply here 23:39, 11 December 2023 (UTC)[reply]
    This could be a good opportunity to check and improve our categorization, too. WhatamIdoing (talk) 02:29, 12 December 2023 (UTC)[reply]

    Black box warnings 2nd project

    Wikipedia talk:WikiProject Medicine#Black box warnings project is largely done.

    As a further goal, I think we should include the text of black box warnings in the drug articles. I propose that a section of each article use a template to pull the text of the warning from wikidata, and that a bot put that section in all of the articles on drugs with boxed warnings. Does that sound like a good idea? a good plan for how to do it? Other ideas? Formatting ideas?.

    (Perhaps a bot isn't needed? If I add a reference here [1], something automatically causes the reference section to appear below, even w/o {{refs}} in a References section. What? Useful? I doubt it, but maybe. Would be cool.)

    (The warning text in Wikidata comes from the FDALabel database.)

    A week ago, here, I proposed/made a request for help with part of this. I wrote in part, The text of each warning is generally concise and consists only of the most import warnings, so it may be worth [importing from the FDALabel database,] storing [in Wikidata] and adding to articles via wikidata. ... No response.

    I was disturbed to find that most drugs with FDA-mandated black box warnings had articles that were missing any mention of the boxes or the risks. It is disturbing to me that many pages mentioned minor side effects but left this critical info out. Part 1 changed this, but there's more to do - adding the text of the warnings.

    -- RudolfoMD (talk) 02:20, 11 December 2023 (UTC)[reply]

    First, I think putting black box information on every drug that has one is important and useful. I'm not sure if there are equivalents of black-box warnings for other regulatory agencies (i.e., other than the US FDA), but if so, I think that should be put on the radar to be addressed once a satisfactory implementation has been found for the FDA-specific black box warnings.
    I do not know much of anything about wikidata, but if there is any way to import that csv from the FDA website into wikidata such that it can be easily referenced, that seems ideal. My complaint before was that the infobox shows that a black box warning exists but there was no readily-available way for the reader to click through to read the text of the warning. There was previous discussion about the fact that medline does have the body of the warnings, and is perhaps easier to link to than the FDA's own data; the point was made that the FDA issues the warnings and so it should be the primary source used for this information. Is there perhaps a way to combine these: have the FDA link in the <ref></ref>, and perhaps also somehow link to the medline entry in the UI in the infobox? This way we link to the primary-source/issuer of the warning, but also provide the utility to the reader of being able to click through and read the warning text easily. Kimen8 (talk) 14:10, 11 December 2023 (UTC)[reply]
    (Perhaps a bot isn't needed? If I add a reference here [1], something automatically causes the reference section to appear below, even w/o {{refs}} in a References section. What? Useful? I doubt it, but maybe. Would be cool.) Whilst {{Reflist}} is invoked even without the template, a bot can check and add the section – though I like to think an article on a drug with a regulatory warning would have references, and therefore already have a reference section. I don't know if the citation style is something a bot is capable of checking. Mentioning as citations should be consistent within a page (but isn't always), but might vary across a project's articles.
    (Have added {{talkref}} below to keep the fake citation within the frame of reference)
    Little pob (talk) 15:22, 11 December 2023 (UTC)[reply]
    Perhaps you missed/misunderstood my proposal, Little pob? I'm wanting all of the articles on drugs with boxed warnings have a section something like:
    === Important Warnings ===
    There's a black box warning about this drug, which reads
    <imported from FDA via Wikidata:> Xoid will kill any patient with foo, and any patient taking Xoid with bar.
    Will a bot be needed to add these -- that is one of my questions - I guess so but perhaps not. RudolfoMD (talk) 03:31, 14 December 2023 (UTC)[reply]
    I think it will be complicated. For example: Clonidine has a black box warning, but only for four injectable formulations, not for the more common tablets, and not even for all injectable formulations. There are four with black box warnings, but they don't give the same black-box warnings. One of them (XGen's) has a warning that "The 500 mcg/mL strength product should be diluted prior to use in an appropriate solution." Maybe the others don't have a 500 mcg/mL product? Both XGen's and PharmaForce's have a warning against using it for childbirth or surgery, but Hikma's injectable formulation doesn't, for no reason that I can discern.
    In principle, I am in favor of including this information, but in practice, I'm not sure that it's feasible. WhatamIdoing (talk) 18:42, 11 December 2023 (UTC)[reply]
    If it's correct, that is annoying - does complicate this. Though I'm guessing and hoping it's rare.
    I'd say Clonidine should say something like:
    There's a black box warning about injectable formulations of this drug, which reads <warning> on the XGen label. In terms of an algorithm: Including the longest warning is most likely to include all the most important warnings.
    Are we sure about this, or are we assuming MedLine is correct? Did you find all the Clonidine labels on fda.gov? RudolfoMD (talk) 03:41, 14 December 2023 (UTC)[reply]
    https://dailymed.nlm.nih.gov/dailymed/ has copies of the Medication package insert submitted to the FDA for all regulated drugs (human and veterinary; does not include unregulated substances, such as herbal supplements). They have 175 entries for clonidine. Seven of the 175 are injectable. These: [4][5][6][7] have one or two boxed warnings (if two, they may be displayed in the same or separate boxes). These do not: [8][9][10], although the first in this box-less batch seems to have an incomplete or incorrectly entered label in the database, and the last two seem to have the same warning about surgical procedures as appears in the boxed warnings. The main difference is that the words aren't displayed in boxes. WhatamIdoing (talk) 04:31, 14 December 2023 (UTC)[reply]
    So does including the longest warning make sense; is anyone volunteering to manually review the warnings so we can see and handle complications like the one with Clonidine as we prepare to display them in wikipedia? RudolfoMD (talk) 05:09, 14 December 2023 (UTC)[reply]
    Passing by comment: can we add a picture to the Boxed warning? I've never heard of this before (I lived in the States for a decade but was never in need of any serious medication...). Skimming that article makes me wonder what that warning actually looks like? Piotr Konieczny aka Prokonsul Piotrus| reply here 03:17, 12 December 2023 (UTC)[reply]
    Passing comment 2: see Talk:Boxed_warning#American_or_global?. We probably need a new article on this concept outside United States, under a more clear name like warnings in drug labels and package or safety information on drug labels (to use some phrasing from cited sources). The current article is appallingly US-centric, and the name is unclear to anyone who is not American. Piotr Konieczny aka Prokonsul Piotrus| reply here 03:25, 12 December 2023 (UTC)[reply]
    All countries have warnings. Only the US seems to have this "extra important warning" thing. The article should be US-centric – as US-centric as the Food and Drug Administration article. WhatamIdoing (talk) 20:21, 12 December 2023 (UTC)[reply]

    References

    1. ^ a b foo bar

    "IL-5 antibody" listed at Redirects for discussion

    The redirect IL-5 antibody has been listed at redirects for discussion to determine whether its use and function meets the redirect guidelines. Readers of this page are welcome to comment on this redirect at Wikipedia:Redirects for discussion/Log/2023 December 11 § IL-5 antibody until a consensus is reached. Best, user:A smart kittenmeow 11:33, 11 December 2023 (UTC)[reply]

    commented--Ozzie10aaaa (talk) 13:50, 16 December 2023 (UTC)[reply]

    "Explaining the Human Body" videos

    explainer video about the thyroid

    Hello! A public broadcaster from Germany, Deutsche Welle, just donated thirteen short English-language explainer videos about general physiology to Commons. You can find them at commons:Category:Creative Commons videos by Deutsche Welle. Do you think any of them could be used in an article? Thank you, --Gnom (talk) 11:51, 12 December 2023 (UTC)[reply]

    some do seem usable and helpful, will look at possible articles, thank you--Ozzie10aaaa (talk) 13:31, 13 December 2023 (UTC)[reply]
    Thank you, Ozzie10aaaa! Please let me know if you have any comments or questions.

    Renaming the mid-level article

    Please see Talk:Mid-level practitioner#Requested move 12 December 2023. WhatamIdoing (talk) 20:21, 12 December 2023 (UTC)[reply]

    Confused about set index articles.

    I was going through some of the disease stubs and found Organ-limited amyloidosis. Since it has so many subtypes, would it be appropriate to turn it into a set index article?

    I'm only asking because the concept of set index articles are new to me and I easily get confused by them.

    CursedWithTheAbilityToDoTheMath (talk) 06:37, 13 December 2023 (UTC)[reply]

    I think everyone is confused by them. The general concept, AIUI, is that Wikipedia:Set index articles are written for a single group of things that are related through both their names and their identity/type (e.g., hurricanes named Bob, but not anything and everything named Bob).
    In terms of writing them, it's partway between a Wikipedia:Disambiguation page and an article, and usually maintains a list structure. In a well-developed SIA, the description of the items are often longer than permissible for a DAB page, and may even lean heavily on Wikipedia:Summary style and {{Main}} links.
    For the specific page you linked, I suspect that SIA is not technically the right model, as it's a general type (like "hurricanes"). That is, the individual items in it are all types of organ-limited amyloidosis (also: types of amyloidosis, types of disease), but they aren't actually called organ-limited amyloidosis under normal circumstances. People would say "Do you remember what happened on the morning that Hurricane Bob struck?", when they mean a specific storm named Bob that happened in a particular year and not any of the other hurricanes named Bob. But people wouldn't normally say "Remember what happened the morning Grandma was diagnosed with organ-limited amyloidosis?" They'd talk about when Grandma was diagnosed with Alzheimer's or Parkinson's or whatever the specific thing is. WhatamIdoing (talk) 16:13, 13 December 2023 (UTC)[reply]
    Thank you! I really appreciate the help. I will just write it as a standard article then. CursedWithTheAbilityToDoTheMath (talk) 20:28, 13 December 2023 (UTC)[reply]

    Brain tumor - Network communication also plays an important role in the spread of the disease

    "It was discovered that the tumor cells communicate with each other in a large network, exchange substances that are essential for survival, and can thus evade the effects of radiation or chemotherapy. Network communication also plays an important role in the spread of the disease. The tumor cells are even networked with healthy nerve cells and receive direct signals from them – in this way, the tumors can grow faster. The mechanisms that are investigated not only offer fundamentally new explanations for the highly aggressive growth of this type of tumor. They also provide approaches for novel therapies – to stop brain tumor growth and make existing therapies more effective. The disruption and even destruction of tumor cell networks is thus becoming a completely new therapeutic principle in oncology, with the first clinical trials building on these findings."

    https://www.krebs-nachrichten.de/personalien-details/deutscher-krebspreis-geht-an-heidelberger-spitzenforscher.html

    Is this new theme useful to show? Wname1 (talk) 09:57, 16 December 2023 (UTC)[reply]

    That is not a reliable source. The relevant MEDRS for this appears to be:
    • Winkler F, Venkatesh HS, Amit M, Batchelor T, Demir IE, et al. (April 2023). "Cancer neuroscience: State of the field, emerging directions". Cell (Review). 186 (8): 1689–1707. doi:10.1016/j.cell.2023.02.002. PMID 37059069.
    and this would certainly be worthy of inclusion somewhere. Bon courage (talk) 10:06, 16 December 2023 (UTC)[reply]
    I wrote it in Brain Tumor. Wname1 (talk) 11:27, 16 December 2023 (UTC)[reply]

    move?

    shouldn't KarXT be moved to something like xanomeline/trospium, similar to dextromethorphan/bupropion? thanks. Biosthmors (talk) 14:53, 19 December 2023 (UTC)[reply]

    yes--Ozzie10aaaa (talk) 13:30, 22 December 2023 (UTC)[reply]

    Verywell Fit and Dotdash Meredith

    I have opened up discussion on the Reliable Sources noticeboard regarding false medical information on the Verywell network of sites. Verywell and content by its parent Dotdash (now called Dotdash Meredith) have previously been blacklisted, but is designated as "no consensus" rather than "unreliable" or "deprecated".

    I have not started an RFC before and would welcome any comments. ScienceFlyer (talk) 20:03, 20 December 2023 (UTC)[reply]

    Physiological prematurity

    Unreferenced stub that has languished for ~15 years now. Can anyone add refs/verify this, or should be WP:TNT it? Piotr Konieczny aka Prokonsul Piotrus| reply here 09:48, 21 December 2023 (UTC)[reply]

    I added a source. WhatamIdoing (talk) 18:52, 21 December 2023 (UTC)[reply]

    William Utermohlen peer review

    Feel free to leave comments for me to improve the William Utermohlen article before I take it to FAC, at Wikipedia:Peer review/William Utermohlen/archive3. Thanks, Realmaxxver (talk) 19:40, 22 December 2023 (UTC)[reply]

    thank you for post--Ozzie10aaaa (talk) 13:30, 27 December 2023 (UTC)[reply]

    Archie Cochrane

    I've added the article about Archie Cochrane as being within the scope of WikiProject Medicine. I hope to improve the article and am open to suggestions about how it can currently be improved. John Desmond (talk) 14:11, 23 December 2023 (UTC)[reply]

    did a few edits--Ozzie10aaaa (talk) 14:03, 24 December 2023 (UTC)[reply]

    Asthma phenotyping and endotyping

    New article on "a novel approach to asthma classification inspired by precision medicine": Asthma phenotyping and endotyping. Any comments regarding WP:MEDRS compliance and/or whether it merits a separate article? AndyTheGrump (talk) 14:15, 23 December 2023 (UTC)[reply]

    @AndyTheGrump, it's probably fine. There are multiple review articles with non-overlapping lists of authors, so we have multiple independent sources. WhatamIdoing (talk) 18:51, 23 December 2023 (UTC)[reply]

    Redirects to asthma types

    Hi, everyone!

    I have recently created the page Asthma phenotyping and endotyping which lists the now-recognised phenotypes and endotypes of asthma. Creating redirects could be helpful, as I don't think many of them deserve their own page at this time.

    However, many redirects to these types already exist, and simply redirect to the Asthma page whole, e.g. Eosinophilic asthma, or only link to the Asthma#Classification page, which doesn't feature them as a classification, e.g. Atopic asthma.

    Do you think something could/should be done about it?

    Thanks for your time! AufbauPrinciple (talk) 10:08, 25 December 2023 (UTC)[reply]

    Is this a good redirect?

    Childhood accidental spiral tibial fracture ==> Toddler's fracture

    Would this be a good idea? On one hand, the article seems to distinguish the two kinds of fractures, while on the other hand, it notes that recent work has considered one a subset of the other. Since the latter is more recent, and obviously they're very similar to the layman, I'm wondering whether it should be left red (either to encourage article creation or to avoid confusion), or whether a redirect would be good, both because they're related and because we want to discourage content forking. The phrase doesn't appear in the body of any other article; its only other appearances, in Bone fracture and Crus fracture, are limited to this citation.[1] Nyttend (talk) 17:59, 27 December 2023 (UTC)[reply]

    1. ^ Mellick LB, Milker L, Egsieker E (October 1999). "Childhood accidental spiral tibial (CAST) fractures". Pediatr Emerg Care. 15 (5): 307–9. doi:10.1097/00006565-199910000-00001. PMID 10532655.
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