Ezetimibe/rosuvastatin
| Combination of | |
|---|---|
| Ezetimibe | Hypolipidemic agent |
| Rosuvastatin | Statin |
| Clinical data | |
| Trade names | Ridutrin,Cholerose Plus, Lipocomb, Rosuzet, others[1][2] |
| AHFS/Drugs.com | Multum Consumer Information |
| License data | |
| Pregnancy category |
|
| Routes of administration | By mouth |
| ATC code | |
| Legal status | |
| Legal status | |
| Identifiers | |
| KEGG | |
Ezetimibe/rosuvastatin, sold under the brand name Ridutrin among others, is a combination medication used to treat high cholesterol.[5][6] In some countries it is sold as a kit or a pack containing two distinct pills.[7][1] It is also available in the form of a composite package containing the two separate pills.[3]
The combination was approved for medical use in the United States in March 2021.[4]
Medical uses
Ezetimibe/rosuvastatin is indicated as an adjunct to diet in people with primary non-familial hyperlipidemia to reduce low-density lipoprotein cholesterol (LDL-C); and alone or as an adjunct to other LDL-C-lowering therapies in people with homozygous familial hypercholesterolemia (HoFH) to reduce LDL-C.[8]
References
- ^ a b "Rosuvastatin international". Drugs.com. 3 February 2020. Retrieved 17 February 2020.
- ^ a b "Ezetimibe/rosuvastatin: List of nationally authorised medicinal products" (PDF). European Medicines Agency (EMA). 21 March 2018. PSUSA/00010271/201707. Retrieved 17 February 2020.
- ^ a b c "TGA eBS - Product and Consumer Medicine Information Licence".
- ^ a b "Roszet: FDA-Approved Drugs". U.S. Food and Drug Administration (FDA). Retrieved 24 March 2021.
- ^ "Ridutrin SmPC" (PDF). Medicines Data Bank. 30 May 2019. Retrieved 17 February 2020.
- ^ Willihnganz MJ, Gurevitz SL, Clayton BD (November 2021). "HMG-CoA Reductase Inhibitor Combination Products". Clayton's Basic Pharmacology for Nurses - E-Book. Elsevier Health Sciences. p. 344. ISBN 978-0-323-81258-0.
- ^ "Rosuzet Composite Pack". NPS MedicineWise. 8 January 2020. Retrieved 17 February 2020.
- ^ Sharretts J (23 March 2021). "NDA Approval Letter for Roszet (rosuvastatin and ezetimibe)" (PDF). Center for Drug Evaluation and Research. U.S. Food and Drug Administration.
External links
- "Ridutrin (rosuvastatin zinc/ezetimibe) Public Assessment Report Scientific discussion" (PDF). NL/H/3017/001-003/DC.
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