Etofibrate

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Etofibrate
Etofibrate.svg
Space-filling model of the etofibrate molecule
Clinical data
AHFS/Drugs.com International Drug Names
ATC code
Pharmacokinetic data
Metabolism Hydrolyzed to clofibric acid and niacin
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
ECHA InfoCard 100.046.115
Chemical and physical data
Formula C18H18ClNO5
Molar mass 363.792 g/mol
3D model (JSmol)
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Etofibrate is a fibrate. It is a combination of clofibrate and niacin, linked together by an ester bond. In the body, clofibrate and niacin separate and are released gradually, in a manner similar to controlled-release formulations.[1]

References[edit]

  1. ^ Sposito AC, Mansur AP, Maranhão RC, Rodrigues-Sobrinho CR, Coelho OR, Ramires JA (2001). "Etofibrate but not controlled-release niacin decreases LDL cholesterol and lipoprotein (a) in type IIb dyslipidemic subjects". Braz J Med Biol Res. 34 (2): 177–82. PMID 11175492. doi:10.1590/S0100-879X2001000200004.  Free full text