OR2B3

OR2B3
Identifiers
Aliases	OR2B3, 6M1-1, OR2B3P, OR6-14, OR6-4, olfactory receptor family 2 subfamily B member 3
External IDs	HomoloGene: 67858; GeneCards: OR2B3; OMA:OR2B3 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) Band 6p22.1 Start 29,086,208 bp End 29,087,313 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle mucosa of transverse colon n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 442184 n/a Ensembl ENSG00000233054 ENSG00000231319 ENSG00000206524 ENSG00000233687 ENSG00000226832 ENSG00000233180 ENSG00000225736 ENSG00000204703 n/a UniProt O76000 n/a RefSeq (mRNA) NM_001005226 n/a RefSeq (protein) NP_001005226 n/a Location (UCSC) Chr 6: 29.09 – 29.09 Mb n/a PubMed search n/a
Wikidata
View/Edit Human

Putative olfactory receptor 2B3 is a protein that in humans is encoded by the OR2B3 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR2B3+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.