From Wikipedia, the free encyclopedia
Jump to: navigation, search
Aliases OR5B12, OR11-241, OR5B12P, OR5B16, OST743, olfactory receptor family 5 subfamily B member 12
External IDs MGI: 3031279 HomoloGene: 133606 GeneCards: 390191
RNA expression pattern
PBB GE OR5B12 gnf1h02108 at tn.png
More reference expression data
Species Human Mouse
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC) Chr 11: 58.44 – 58.44 Mb Chr 19: 12.88 – 12.88 Mb
PubMed search [1] [2]
View/Edit Human View/Edit Mouse

Olfactory receptor 5B12 is a protein that in humans is encoded by the OR5B12 gene.[3][4]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also[edit]


  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Fuchs T, Malecova B, Linhart C, Sharan R, Khen M, Herwig R, Shmulevich D, Elkon R, Steinfath M, O'Brien JK, Radelof U, Lehrach H, Lancet D, Shamir R (Sep 2002). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199. 
  4. ^ a b "Entrez Gene: OR5B12 olfactory receptor, family 5, subfamily B, member 12". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.