OR4K1

OR4K1
Identifiers
Aliases	OR4K1, OR14-19, olfactory receptor family 4 subfamily K member 1
External IDs	MGI: 3030562; HomoloGene: 74224; GeneCards: OR4K1; OMA:OR4K1 - orthologs
Gene location (Human) Chr. Chromosome 14 (human) Band 14q11.2 Start 19,930,917 bp End 19,936,757 bp
Gene location (Mouse) Chr. Chromosome 14 (mouse) Band 14|14 C1 Start 50,371,215 bp End 50,380,137 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gallbladder n/a More reference expression data BioGPS n/a
Gene ontology Molecular function transmembrane signaling receptor activity olfactory receptor activity signal transducer activity G protein-coupled receptor activity Cellular component membrane integral component of membrane plasma membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79544 258039 Ensembl ENSG00000155249 ENSMUSG00000050030 UniProt Q8NGD4 Q7TRM6 RefSeq (mRNA) NM_001004063 NM_001011809 RefSeq (protein) NP_001004063 NP_001011809 Location (UCSC) Chr 14: 19.93 – 19.94 Mb Chr 14: 50.37 – 50.38 Mb PubMed search
Wikidata
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Olfactory receptor 4K1 is a protein that in humans is encoded by the OR4K1 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.