OR8B12

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OR8B12
Identifiers
AliasesOR8B12, OR11-317, olfactory receptor family 8 subfamily B member 12
External IDsMGI: 3030708 HomoloGene: 17377 GeneCards: OR8B12
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for OR8B12
Genomic location for OR8B12
Band11q24.2Start124,539,635 bp[1]
End124,545,333 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001005195

NM_146882

RefSeq (protein)

NP_001005195

NP_667093

Location (UCSC)Chr 11: 124.54 – 124.55 MbChr 9: 37.75 – 37.75 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 8B12 is a protein that in humans is encoded by the OR8B12 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000170953 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000063350 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ a b "Entrez Gene: OR8B12 olfactory receptor, family 8, subfamily B, member 12".

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.