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CDP-paratose synthase

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CDP-paratose synthase
Identifiers
EC no.1.1.1.342
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins

CDP-paratose synthase (EC 1.1.1.342, rfbS (gene)) is an enzyme with systematic name CDP-alpha-D-paratose:NADP+ 4-oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction

CDP-alpha-D-paratose + NADP+ CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + NADPH + H+

This enzyme participates in synthesis of paratose and tyvelose.

References

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  1. ^ Verma N, Reeves P (October 1989). "Identification and sequence of rfbS and rfbE, which determine antigenic specificity of group A and group D salmonellae". Journal of Bacteriology. 171 (10): 5694–701. PMC 210416. PMID 2793833.
  2. ^ Hallis TM, Lei Y, Que NL, Liu H (April 1998). "Mechanistic studies of the biosynthesis of paratose: purification and characterization of CDP-paratose synthase". Biochemistry. 37 (14): 4935–45. doi:10.1021/bi9725529. PMID 9538012.
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