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DNA replication gene dnaC
OrganismEscherichia coli
(str. K-12 substr. MG1655)
RefSeq (Prot)NP_418781.1
Other data
EC number2.7.7.7
Chromosomegenome: 4.6 - 4.6 Mb

dnaC is a loading factor for helicase dnaB.[1] dnaB and dnaC associate with the dnaA bound origin.[1] After loading dnaB at the origin, dnaC is released.[1]

This interaction of dnaC with dnaB requires the hydrolysis of ATP.[2]


  1. ^ a b c Slonczewski JL, Foster JW, Gillen KM (2009). Microbiology: an evolving science (1st ed.). New York: W.W. Norton & Co. ISBN 978-0-393-97857-5.
  2. ^ Kobori JA, Kornberg A (November 1982). "The Escherichia coli dnaC gene product. III. Properties of the dnaB-dnaC protein complex". The Journal of Biological Chemistry. 257 (22): 13770–5. PMID 6292205.

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