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DNA replication gene dnaC
Organism Escherichia coli
(str. K-12 substr. MG1655)
Symbol dnaC
Entrez 948864
RefSeq (Prot) NP_418781.1
UniProt P0AEF0
Other data
EC number
Chromosome genome: 4.6 - 4.6 Mb

dnaC is a loading factor for helicase dnaB.[1] dnaB and dnaC associate with the dnaA bound origin.[1] After loading dnaB at the origin, dnaC is released.[1]

This interaction of dnaC with dnaB requires the hydrolysis of ATP.[2]


  1. ^ a b c Slonczewski, Joan, and John Watkins. Foster. Microbiology: An Evolving Science. New York: W.W. Norton &, 2009. Print.
  2. ^ Kobori JA, Kornberg A (November 1982). "The Escherichia coli dnaC gene product. III. Properties of the dnaB-dnaC protein complex". J. Biol. Chem. 257 (22): 13770–5. PMID 6292205. 

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